Project Grant R21AI196537
- Federal Grant Award Summary The University of Pittsburgh received a $437,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 25, 2025, with a completion date of June 30, 2027. The grant supports research targeting host nuclear receptors for resolving Staphylococcus aureus skin infections, specifically methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue...
- Federal Grant Award Summary The University of Pittsburgh received a $1.455 million Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 3, 2025, with completion targeted for May 31, 2030. This award supports innovative immunological research designed to extend kidney allograft survival and enable immunosuppressive drug withdrawal in nonhuman primates (rhesus macaques). The...
- Federal Project Grant Award Summary The University of Pittsburgh received a $556,843 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 16, 2025, with a completion date of June 30, 2030. This grant supports basic immunology research investigating the development and regulation of the extrafollicular (EF) B cell response as a programmed immune response type. The research aims...
- Summary of Federal Project Grant Award The University of Pittsburgh received a $547,988 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 11, 2025, with a completion date of July 31, 2030. The award supports research and development of a novel monkeypox virus (MPXV) vaccine delivery system utilizing microneedle patch technology. The project focuses on testing a...
- Federal Grant Award Summary The University of Pittsburgh received a $452,835 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective February 2, 2026 through January 31, 2028. This award funds research to develop novel therapeutic approaches targeting innate immune memory (IMEM) responses that drive T cell-mediated rejection (TCMR) in organ transplant recipients. The research will...
- Federal Grant Award Summary The University of Pittsburgh received a $2,976,652 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2029. This award supports research investigating polyamine toxicity and resistance mechanisms in two epidemic bacterial skin pathogens: methicillin-resistant Staphylococcus aureus (MRSA) and Streptococcus pyogenes...
- Federal Grant Award Summary The University of Pittsburgh received a $437,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) for a project period spanning February 4, 2026 through January 31, 2028. The award funds the development and evaluation of a rationally designed bacteriophage (phage) cocktail to treat multidrug-resistant (MDR) Pseudomonas aeruginosa infections. The primary...
- Federal Grant Award Summary The University of Pittsburgh received a $430,760 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 10, 2025, with completion scheduled for June 30, 2027. The project, titled "Training of Neutrophils to Defend Against a Lethal Bacterial Infection of the Lung," focuses on developing immunological strategies to enhance host defense against...
- Federal Project Grant Award Summary The University of Pittsburgh received a $209,408 Project Grant awarded September 19, 2025, by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The research project, "Early T Cell Responses in Tuberculosis," is scheduled for completion by August 31, 2030, and will be conducted at the University of Pittsburgh's Pennsylvania campus. This award funds basic...
- Federal Grant Award Summary The University of Pittsburgh received a $412,942 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 5, 2026, with completion targeted for January 31, 2028. This developmental research initiative investigates the regulatory mechanisms by which host-derived environmental signals in the gastrointestinal tract control hypervirulent Klebsiella...
The University of Pittsburgh received a $437,250 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 23, 2026, with completion targeted for January 31, 2028. This grant supports the development of a skin immunization platform (SIP) utilizing metal-organic framework (MOF)-based nanovaccine constructs combined with needle-free microneedle arrays (MNAs) to enhance the immunogenicity and efficacy of subunit antigen vaccines. The research deliverables include the design and characterization of rapidly separable microneedle arrays (RSMNAs) that enable vaccine implantation into skin in under 10 seconds, addressing limitations of traditional subunit vaccines through innovative delivery technology and clinically de-risked adjuvants. The project will generate scientific and technical products focused on demonstrating that skin-targeted MOF vaccine constructs can generate robust, durable antigen-specific humoral and cellular immune responses in a well-tolerated manner. The University of Pittsburgh's research infrastructure in Pittsburgh, Pennsylvania will support preclinical vaccine development, characterization of immunological mechanisms, and comparative evaluation of the SIP platform against conventional vaccine delivery approaches, ultimately contributing to more accessible and deployable vaccine technologies for global health applications.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $437.3k | 2/23/26 |