Project Grant R21AI196335
- Federal Project Grant Award Summary National Jewish Health received a $429,546 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded August 8, 2025, with completion targeted for July 31, 2027. The grant funds research to develop improved preclinical measures for evaluating tuberculosis (TB) treatment regimen efficacy by utilizing transcriptomic analysis rather than traditional...
- Federal Project Grant Award Summary National Jewish Health received a $702,103 Project Grant from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837), effective September 1, 2025, through June 30, 2029. This award funds research to elucidate the molecular mechanisms by which the SFTA2 (Surfactant Associated Protein 2) protein interacts with the ADGRF5 (Adhesion G Protein-Coupled Receptor F5) signaling pathway to regulate alveolar...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded a Project Grant of $566,875 to the La Jolla Institute for Immunology under the Allergy and Infectious Diseases Research program (CFDA 93.855) on February 18, 2026, with a completion date of January 31, 2028. Under this award, Dr. Vijayanand's research team will conduct scientific research to deorphanize a novel G-protein coupled receptor (GPCR) expressed by tissue-resident memory T cells (TRM...
- Federal Project Grant Award Summary This Project Grant, awarded on March 1, 2025, by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $389,480 in funding to Boston Children's Hospital for a five-year research initiative (completion date: February 28, 2030). The award supports fundamental immunological research investigating the establishment of lung-resident, self-antigen-specific CD4+...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded $730,392 to The Regents of the University of Colorado (University of Colorado-Denver) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on June 17, 2025, with a completion date of May 31, 2030. This five-year Project Grant funds basic and translational research investigating adipocyte-eosinophil communication and its regulatory role in airway function, with...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Massachusetts General Hospital a $250,000 Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective August 1, 2025, through July 31, 2026. This award supports investigator-initiated biomedical research focused on identifying therapeutic targets for allergic asthma treatment. The research project examines lung-resident memory Type 2 helper T cells...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Colorado-Denver a Project Grant of $802,499 under the Allergy and Infectious Diseases Research program (CFDA 93.855) effective September 17, 2025, with a completion date of August 31, 2030. This five-year research initiative focuses on identifying genetic factors contributing to tuberculosis (TB) susceptibility in African populations by integrating genomic architecture with...
- Federal Project Grant Award Summary Boston Children's Hospital received a $489,500 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025, through July 31, 2027. The award funds the development of human cellular models to advance understanding of tuberculosis (TB) infection and innate immune responses. Specifically, the research will establish a physiological...
- Federal Project Grant Award Summary Tufts University School of Medicine received a $156,080 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded January 29, 2026, with completion targeted for August 15, 2028. The grant funds research investigating the spatio-temporal modulation of innate immune cells in relation to Mycobacterium tuberculosis (MTB) stress response and replication...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Massachusetts General Hospital $453,750 on June 17, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855) to develop an innovative high-throughput airway organoid screening platform. This research project, scheduled for completion by May 31, 2027, focuses on identifying novel mechanisms of communication between airway epithelial cells (AECs) and intraepithelial...
National Jewish Health received a $470,219 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 5, 2026, with a completion date of January 31, 2028. The award funds biomedical research investigating the role of resident memory T (TRM) cells in chronic obstructive pulmonary disease (COPD) pathogenesis and recurrent viral infections. The research project examines how fatty-acid binding protein 5 (FABP5) regulates lung TRM cell function and mitochondrial metabolism, with the objective of uncovering novel therapeutic targets to reduce susceptibility to recurrent influenza virus infections in COPD patients. The deliverables from this project-based research award include scientific findings from murine model studies evaluating TRM cell dysfunction in cigarette smoke-exposed lungs and investigating the sufficiency of FABP5 for maintaining TRM cell metabolic survival and function. The research is designed to generate evidence-based knowledge regarding cellular and molecular mechanisms underlying recurrent infections in COPD, potentially identifying new cell types and signaling pathways for therapeutic intervention to slow disease progression in this currently incurable condition.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $470.2k | 2/4/26 |