The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $236,292 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to Tufts University School of Medicine to characterize the structures of key herpes simplex virus (HSV) glycoprotein complexes involved in viral entry. The goal is to leverage new methods to isolate and analyze these glycoprotein complexes, providing high-resolution structural "snapshots" that can help elucidate the mechanisms of HSV cell entry. This knowledge will open new opportunities for the rational design of HSV vaccines and therapeutics. The project will run from February 1, 2025 to January 31, 2027.
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