The University of Texas Southwestern Medical Center received a $246,000 Project Grant from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) to determine the optimal sampling and test methods for using polymerase chain reaction (PCR) diagnostics to detect congenital syphilis in neonates. The research aims to identify the best specimen types and gene targets for maximizing the sensitivity and specificity of PCR testing to improve diagnosis and treatment of congenital syphilis, which is rising in prevalence and can have severe consequences for newborns if not properly identified and managed. This 2-year grant project will leverage the expertise of a multidisciplinary research team specializing in maternal-fetal medicine, neonatology, pediatric infectious diseases, and molecular diagnostics.
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