This Project Grant award from the National Institute of Allergy and Infectious Diseases (CFDA 93.855 - Allergy and Infectious Diseases Research) totaling $517,038 will enable the development and evaluation of enhanced swab sampling methods for high-sensitivity tongue swab testing to detect active tuberculosis (TB). The project aims to: 1) Develop and assess high-capacity oral swab testing for pulmonary TB, and 2) Develop and assess protocols for testing serially collected and pooled oral swab samples for TB screening. This non-invasive approach has the potential to simplify TB diagnosis, improve patient care, and enable active case-finding strategies to reduce TB transmission globally. The funding will support research activities at the University of Washington from June 2024 through April 2026.
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