The National Institute of Allergy and Infectious Diseases (NIAID), under CFDA 93.855 Allergy and Infectious Diseases Research, awarded a $189,150 Project Grant to the University of Colorado-Denver. The funding will support an exploratory project to identify new mediators of proinflammatory cytokine signaling, such as interleukin-1 beta and tumor necrosis factor alpha, and how they disrupt Akt cellular signaling pathways. The research will leverage genome-wide genetic screens and validation studies to gain mechanistic insights into cytokine-induced inhibition of important cellular processes. If successful, this project could provide key insights to inform the development of new therapeutics for cytokine-linked diseases. The award period runs from Nov 13, 2024 to Oct 30, 2026.
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