The University of Chicago was awarded a $467,400 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855). The grant supports research to identify protective antigens of Staphylococcus aureus and the T cell and B cell responses that lead to decolonization of this pathogen. The researchers will exploit the observation that mice lacking the MHC-II regulator H2-O show enhanced antibody responses against S. aureus, with the goal of developing new approaches to reduce burdens imposed by this recurrent human pathogen. The award period is from Jul 12, 2024 to May 31, 2026.
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