Project Grant R21AG098947
- Federal Project Grant Award Summary The University of Utah received a $437,252 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866) to develop and validate a plasma biomarker for TDP-43 proteinopathy. The award, effective January 1, 2026 through December 31, 2030, supports research investigating the relationship between TDP-43 (TAR DNA-binding protein of 43 kDa) pathology and neurodegeneration in Alzheimer's disease and frontotemporal lobar...
- Federal Project Grant Summary The University of Utah received a $603,165 Project Grant from the National Institute on Aging (CFDA 93.866 – Aging Research) awarded February 15, 2026, with a completion date of February 14, 2029. The research project examines the cognitive-motor processes underlying volitional stepping in younger and older adults to optimize fall prevention interventions. The study will recruit 60 participants (30 younger and 30 older adults) to complete a clinically validated...
- Federal Project Grant Award Summary The National Institute on Aging awarded a $749,108 Project Grant to the University of California, Irvine on May 15, 2025, under the Aging Research program (CFDA 93.866) to conduct research examining the relationship between memory failures and decision-making impairment in older adults through May 2030. The project delivers integrated computational and neuroscientific research services designed to understand how different types of memory—including item memory,...
- Federal Grant Award Summary The National Institute on Aging awarded the University of Rochester a $641,856 Project Grant beginning September 1, 2025, under the Aging Research program (CFDA 93.866) to conduct research examining the effects of declining nursing home capacity on post-acute and long-term care access and health outcomes among older adults and their caregivers. The research addresses a critical evidence gap regarding nursing home capacity shortages that have emerged following the...
- Federal Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded The Washington University a Project Grant of $2,631,670 effective September 1, 2025, through August 31, 2029. This research initiative investigates age-related deficits in episodic memory for both the content and structure of naturalistic events, with particular focus on understanding memory loss mechanisms in aging and Alzheimer's disease (AD). The project will deliver...
- Federal Grant Award Summary The National Institute on Aging awarded The Johns Hopkins University a $1.75M Project Grant on May 15, 2025, under the Aging Research program (CFDA 93.866) to develop and apply statistical methods that improve scientific inferences in Alzheimer's Disease (AD) research. The primary deliverables include methodological innovations and computational tools designed to better model, estimate, and predict disease incidence risk and longitudinal biomarker outcomes in...
- Federal Grant Award Summary Northwestern University's Sponsored Research Division received a $640,000 Project Grant from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective September 1, 2025, through August 31, 2027. The award funds the "Study to Understand Participant Perspectives on Respite Uptake (SUPPORT)," a qualitative research initiative addressing the low utilization of Adult Day Services (ADS) among family caregivers of individuals...
- Federal Project Grant Award Summary The National Institute on Aging (NIA), under the Aging Research program (CFDA 93.866), awarded a $643,089 project grant to the University of Massachusetts Medical School to conduct an objective assessment of medication self-administration (MSA) as an early indicator of cognitive impairment and Alzheimer's disease and related dementias (ADRD). Commencing September 30, 2025, and concluding August 31, 2026, the research leverages the Framingham Heart Study cohort...
- Federal Grant Award Summary S-3 Research LLC received a $999,556 Project Grant from the National Institute on Aging under the Aging Research program (CFDA 93.866) for the period of September 20, 2025, through September 19, 2026. The award supports the development of a multi-modal digital tool designed to improve diversity and inclusion in Alzheimer's Disease and Related Dementias (AD/ADRD) clinical trial participation. The deliverables include a clinical trial matching algorithm specific to ADRD...
- Federal Project Grant Award Summary The National Institute on Aging (NIA) awarded the University of Alabama at Birmingham $5,057,416 under the Aging Research program (CFDA 93.866) on September 15, 2025, for a four-year project completing September 14, 2029. This Project Grant supports research examining the impact of undiagnosed Alzheimer's Disease and Related Dementias (ADRD) on healthcare utilization across geographic regions in the United States. The research directly addresses implementation...
The University of Utah's Office of Sponsored Projects received a $423,500 Project Grant award from the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), effective April 15, 2026, with completion targeted for March 31, 2028. This award supports research addressing decision-making capacity assessment and inclusive decision-making practices for older adults with cognitive impairments. The project responds to the escalating prevalence of Alzheimer's disease and related dementias among the aging population—currently affecting an estimated 6.9 million Americans with projections reaching 12.7 million by 2050—by examining how clinicians assess decision-making capacity and implement informed consent procedures. The research deliverables focus on evaluating whether current clinical capacity assessment approaches align with evolving legal and policy frameworks that emphasize supported decision-making and autonomy rights rather than surrogate decision-making models. The project addresses identified gaps in clinical practice, including poor interrater reliability in capacity assessments, risks of bias, and the dichotomous nature of traditional capacity determinations. The research conducted at the Salt Lake City facility will generate evidence-based findings on capacity assessment practices in clinical settings and provide recommendations for integrating contemporary legal and ethical standards into clinical protocols for managing healthcare and personal decisions for individuals with decisional impairments.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $423.5k | 4/17/26 |