This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $431,750 to Rutgers, The State University of New Jersey to identify molecular features associated with vascular alterations in aging. The project aims to isolate and characterize peptide ligands targeting vascular endothelial cells in young versus aged mice, as well as senescent versus non-senescent murine cells in vitro. This innovative approach leverages in vivo phage display to study age-related vascular dysfunction, with the potential to inform the development of senolytic drugs or targeted strategies for age-related vascular diseases. The project period runs from January 1, 2025 to December 31, 2026.
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