Project Grant R21AG091008
- The National Institute on Aging (NIA) awarded a $713,723.32 Project Grant under the Aging Research Federal Grant Program (CFDA 93.866) to the Albert Einstein College of Medicine in Bronx, NY. The award, effective from February 1, 2025 to January 31, 2028, will support research on the influence of neighborhood characteristics, both objective and subjective, as well as GPS-based personal activity space measures, on cognitive decline, Alzheimer's disease and related dementias (ADRD), and...
- This $428,397 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports a multi-year research study on the anatomical and functional characteristics of the thymus in the elderly human population. The research team at the University of Pikeville will conduct qualitative and quantitative assessments of thymic structure and function in cadaver samples, using techniques such as immunohistochemistry and molecular biology to determine the degree of thymic...
- The National Institute on Aging (NIA), through its Aging Research federal grant program (CFDA 93.866), awarded a $636,342 Project Grant to Trustees of Boston University (doing business as Boston University Medical Campus) to conduct research on normal and pathological brain aging. The grant, with a performance period from August 1, 2025 to April 30, 2030, will support a multiscale modeling and empirical study of progressive myelin dystrophy, loss of synapses, and neuronal hyperexcitability in...
- This $2,591,620 Project Grant was awarded by the National Institute on Aging (NIA) under the Aging Research federal grant program (CFDA 93.866) to Cedars-Sinai Medical Center in California. The grant is designed to determine the role of hypothalamic neurons in the progression of physiological decline with age, with a focus on understanding the cellular mechanisms responsible for increased frailty in older adults. Key objectives include elucidating the role of arginine-vasopressin (AVP) neurons...
- This federal Project Grant award of $145,566 from the National Institute on Aging (CFDA 93.866 - Aging Research) is supporting research at the Icahn School of Medicine at Mount Sinai to investigate how the brain accumulates and utilizes "cognitive maps" - internal neural representations that enable flexible behavior and memory recall. The research aims to provide insights into the neuronal coding deficits underlying cognitive decline, with the goal of informing therapeutic...
- This $789,664 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will support a research project titled "Dissecting the Cellular and Spatial Tissue Clock of the Human Lung and Peripheral Blood" at the Icahn School of Medicine at Mount Sinai. The project aims to leverage single-cell RNA sequencing and spatial transcriptomics to characterize the effect of age on the cellular microenvironment of the human lung and peripheral blood. The research will...
- The National Institute on Aging (NIA) awarded a $442,357 Project Grant under the Aging Research program (CFDA 93.866) to the Research Foundation of the City University of New York (RFCUNY) on December 15, 2024. The grant aims to elucidate the molecular mechanisms that give rise to functionally neurodegenerative microglia, the brain's primary innate immune cells, which have been implicated as major determinants of Alzheimer's disease (AD) risk. The research will leverage novel mouse models and...
- The National Institute on Aging (NIA), under the Aging Research federal grant program (CFDA 93.866), awarded a Project Grant in the amount of $4,035,962.00 to the Icahn School of Medicine at Mount Sinai (ISMMS) on September 15, 2025. The grant is titled "Examining Unique Markers and Risk Factors for AD/ADRD in Foreign- and Native-Born Older Chinese Americans: A Study of Social Determinants of Health, Sleep Patterns, Neuroimaging, and Plasma Biomarkers." The project aims to...
- This federal Project Grant award of $2,631,670 from the National Institute on Aging (CFDA 93.866 Aging Research) supports a research initiative at The Washington University to investigate age-related deficits in episodic memory. The project aims to determine how aging distinctly affects the content and structure of memory representations, and how this relates to dysfunction in different brain networks based on susceptibility to Alzheimer's disease pathology. The research will utilize plasma...
- The National Institute on Aging (CFDA 93.866 Aging Research) awarded a $506,000 Project Grant to the Scripps Research Institute to engineer a novel biomolecular condensate (BMC)-based tool with tunable physicochemical properties. The goal is to create an orthogonal selective autophagy receptor (SAR)-like BMC capable of supporting autophagosome biogenesis and selective cargo recruitment. This will enable detailed investigation of the biophysical regulatory mechanisms of BMCs in autophagy, which...
The National Institute on Aging awarded a $462,000 Project Grant to the Albert Einstein College of Medicine in Bronx, NY on August 15, 2025 under the Aging Research federal grant program (CFDA 93.866). The grant supports a two-year research project to map the intrathymic trajectory of β-adrenergic innervation and investigate its role in age-dependent thymic involution. The research aims to create a comprehensive spatial map of β-adrenergic nerve distribution within the thymic stromal network and experimentally modulate β-adrenergic signaling to assess its impact on thymus structure and function. Additionally, the project will utilize the methodological resources from the first aim to characterize the role of β-adrenergic innervation in thymic involution during aging. The ultimate completion date for this project is July 31, 2027.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $462.0k | 8/8/25 |