The National Institute on Aging (NIA) awarded a $237,763 Project Grant under the Aging Research program (CFDA 93.866) to Northeastern University to develop a genome-scale CRISPR activation toolkit for systematically identifying genes that modulate lifespan and health in the model organism C. elegans. The research aims to overcome technological limitations in previous gene overexpression studies and enable rapid, targeted activation of specific genes across the C. elegans genome. This innovative approach is expected to reveal new genetic determinants of longevity and health, with potential applications for understanding and treating age-related diseases. The 2-year project period runs from May 1, 2024 to April 30, 2026.
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