Project Grant R15NS139201
- This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research to investigate the role of inhibitory synaptic nanostructure in inhibitory synaptic plasticity. The total award amount is $110,574.00 and the period of performance is from July 14, 2025 to November 30, 2027. The research will be conducted by the University of Colorado-Denver,...
- The University of Chicago received a $433,592 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award will fund research to assess the conditions under which long-term depression (LTD) is evoked in the cerebellum of intact mice. Specifically, the researchers will investigate how ramping activity in granule cell and Purkinje cell neurons...
- This federal Project Grant award in the amount of $458,806.00 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The grant will support research conducted by the University of Chicago to characterize the fundamental differences between projection and local pathways in proprioceptive signaling in Drosophila larvae. Key activities include using advanced...
- The National Institute of Neurological Disorders and Stroke (NINDS), part of the U.S. Department of Health and Human Services, awarded a $663,942 Project Grant to Yale University under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program. The grant, awarded on July 25, 2025 with an ultimate completion date of June 30, 2030, supports research to examine the interplay between the synaptic proteins complexin and synaptotagmin and their...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $404,340 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Georgia Research Foundation, Inc. The project aims to develop a novel method using split fluorescent protein tags to map the localization of neurotransmitter receptors within neural circuits in the Drosophila model organism. This work will provide crucial new insights into the...
- This federal Project Grant award, valued at $147,486, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of this award is to investigate the function of a ciliary protein in neural development, with a focus on uncovering novel molecular mechanisms involved in synapse formation that may be relevant to neurological disorders. Using C. elegans as...
- This $108,486 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research at the University of Florida focused on exploring the role of the nonmuscle myosin IIB (NMIIB) motor protein in regulating synaptic actin dynamics. The research aims to elucidate how NMIIB contributes to structural plasticity in dendritic spines, which is...
- This Project Grant award of $387,525 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research to investigate the role of proton-mediated signaling at the neuromuscular junction in amyotrophic lateral sclerosis (ALS) models. The research aims to study how dysregulation of extracellular proton (pH) concentrations may contribute to the progression of ALS in...
- This $270,434 federal Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the mechanistic link between spatiotemporal regulation of mRNA and neuronal remodeling during morphogenesis. The principal investigator will use Drosophila mushroom body and dendritic arborization neurons as models to study the...
- This Project Grant award, valued at $481,250.00 and provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to develop a synthetic biological system to manipulate subcellular RNAs and proteins in growth cones or synapses of subtype- and context-specific neurons. The goal is to enable unique forms of subcellular functional investigation in subtype- and...
This federal Project Grant award of $515,078 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Grinnell College to investigate the role of pH in presynaptic homeostatic potentiation at the vertebrate neuromuscular junction. The project, running from September 2025 to August 2028, involves Grinnell College faculty and undergraduate students in all aspects of the research. Key objectives include measuring pH changes in the synaptic cleft during presynaptic homeostatic potentiation and understanding the mechanism by which inhibition of acetylcholine receptors lowers pH in the cleft. The research aims to advance understanding of synaptic transmission and homeostatic regulation at the neuromuscular junction.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $515.1k | 8/27/25 |