Project Grant R15ES038679
- The National Institute of Environmental Health Sciences awarded the University of Cincinnati $698,212 on April 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate the impact of micro- and nanoplastics on cardiac toxicity and heart disease susceptibility. The research addresses mechanisms by which micro- and nanoplastics cause cardiac damage, focusing on mitochondrial dysfunction and oxidative stress in the heart. Preliminary findings show that exposure to micro- and...
- The National Institute of Environmental Health Sciences awarded New York University $10.907 million on September 15, 2025, under the Environmental Health program (CFDA 93.113) to conduct a translational study on the accumulation of micro- and nanoplastic particles in mammalian tissues. The research investigates inter-tissue accumulation of micro- and nanoplastic particles across the lifespan, including the quantified concentration of these particles within systemic tissues, the role of sex, age,...
- The National Institute of Environmental Health Sciences awarded $114,072 to Rutgers The State University of New Jersey, School of Nursing, on September 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate mechanisms of micro-nanoplastics uptake, translocation, and toxicity in in vitro human intestinal models. The research explores how micro-nanoplastics—small plastic particles from environmental breakdown of waste—enter and cross biological barriers, particularly the...
- The National Institute of Environmental Health Sciences awarded the Board of Regents of the University of Nebraska $1,479,178 on September 9, 2025, under the Environmental Health program (CFDA 93.113) to quantify the release of nano- and microplastics from plastic food containers into water and beverages and assess potential health risks. The project measures the release of nano- and microplastics from reusable plastic cups, single-use water and soft drink bottles, and takeaway coffee cups...
- The National Institute of Environmental Health Sciences awarded Morgan State University $142,399 on August 7, 2026, under the Environmental Health program (CFDA 93.113) to investigate the cardiac effects of weathered microplastics through aligned in vitro, ex vivo, and in vivo experimental systems. The research tests whether environmentally realistic weathered microplastics induce distinct and potentially more harmful biological effects on mammalian hearts than pristine microplastics....
- The University of Central Florida Board of Trustees received a five-year, $500,000 Project Grant award from the National Science Foundation to support research titled "CAREER: ELUCIDATION OF THE PHYSICAL PRINCIPLES THE GOVERN ENDOTHELIAL STRUCTURE AND FUNCTION." The award was issued on March 1, 2021 under the National Science Foundation's Engineering program (CFDA 47.041). Through this funding, researchers at the University of Central Florida's Office of Research will investigate the...
- The National Institute of Environmental Health Sciences awarded the University of New Mexico Health Sciences Center $167,928 under the Environmental Health Project Grant program (CFDA 93.113) on April 1, 2026. The project investigates lipoprotein-mediated nanoplastic uptake and transport across the placenta. The research addresses how micro and nanoplastics translocate into placental tissue and the role chylomicrons may play in facilitating this process. The working hypothesis posits that...
- The National Institute of Environmental Health Sciences awarded $765,348 to the University of California, Davis on April 14, 2026, under the Environmental Health program (CFDA 93.113) to investigate pollutant-adsorbed nanoplastics and their health impacts following inhalation exposure. The research addresses the formation, distribution, and neurotoxic effects of composite particles created when airborne pollutants adsorb onto nanoplastics. The study employs advanced label-free imaging...
- The National Institute of Environmental Health Sciences, part of the Department of Health and Human Services National Institutes of Health, awarded the University of South Carolina $140,048 on August 7, 2026, under the Environmental Health program (CFDA 93.113) for a Project Grant (R03ES037766) to investigate microplastic biodistribution and mental health impacts during inflammatory bowel disease. The research assesses how microplastic consumption affects an animal model of inflammatory bowel...
- The National Institute of Environmental Health Sciences awarded New Jersey Institute of Technology $759,977 for a Project Grant (R56ES037652) on September 1, 2026, under the Environmental Health program (CFDA 93.113). The award funds investigation of placental translocation and toxicity of environmentally relevant nanoplastics—plastic particles smaller than one micron that accumulate in human organs and may disrupt health during sensitive developmental windows. NJIT will study placental toxicity...
The National Institute of Environmental Health Sciences awarded The University of Central Florida Board of Trustees $442,580 on September 1, 2026, under the Environmental Health program (CFDA 93.113) to investigate microplastic-induced mechanobiological dysfunction in the vascular endothelium. The recipient will conduct a three-year study characterizing how microplastic exposure impairs endothelial cell mechanical integrity and function under physiologically relevant flow conditions. Aim 1 employs traction force microscopy and cell adhesion assays to measure microplastic effects on endothelial cell-matrix adhesion. Aim 2 uses immunofluorescence, Western blot analysis, and gene expression studies to characterize disruption of shear stress-activated mechanotransduction signaling pathways under controlled flow. Aim 3 evaluates endothelial barrier dysfunction and tests therapeutic interventions using clinically relevant antioxidants and anti-inflammatory compounds. The research exposes human aortic and umbilical vein endothelial cells to environmentally relevant concentrations of polystyrene and polyethylene microplastics using laminar and disturbed flow chambers and comprehensive barrier function analysis. Performance occurs at UCF's Orlando, Florida location from September 1, 2026, through August 31, 2029. This Project Grant supports NIEHS's mission to research how environmental factors affect biological systems and translate findings to reduce disease and promote health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $442.6k | 8/31/26 |