Project Grant R15DK144838
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $377,986 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the University of Northern Colorado. The grant funds a 3-year research project to evaluate the therapeutic effects of the non-psychoactive cannabinoids cannabigerol (CBG) with or without cannabidiol (CBD) in alleviating the symptoms of diet-induced non-alcoholic fatty liver disease (NAFLD) and...
- This Project Grant award of $1,982,628.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The grant supports research to develop advanced methods for detecting liver fibrosis and creating a predictive diagnostic model for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) in primary care settings. The project aims to improve identification of...
- This federal Project Grant award in the amount of $1,428,186.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), to Beth Israel Deaconess Medical Center, Inc. (Bidmc) in Massachusetts. The project aims to investigate the role of CYP4F enzymes in regulating N-acyl amino acid signaling in humans, which has implications for understanding the early...
- This $2,638,760.00 Project Grant award was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The research aims to investigate a novel mechanism involving the metabolite rhodoquinone (RQ) and its potential role in improving mitochondrial function and mitigating metabolic diseases caused by obesity. Specifically, the project will elucidate how the RQ/fumarate...
- This $824,655 Project Grant award from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research aimed at understanding the role of sex-biased transcription factors in conferring protection against metabolic dysfunction-associated steatotic liver disease (MASLD) in females. The research will use adult-onset, hepatocyte-specific knockdown technology to elucidate...
- This federal Project Grant award from the U.S. Department of Agriculture's (USDA) Agriculture and Food Research Initiative (AFRI) program provides $300,000.00 to Oklahoma State University (OSU) to conduct research on the role of the endocannabinoid system in the gut-liver axis and its impact on non-alcoholic fatty liver disease (NAFLD). The two-year project aims to identify molecules and mechanisms that contribute to NAFLD development via the gut-liver connection, with a focus on understanding...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $776,863 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to the Regents of the University of Michigan. The award will fund a multi-ancestry whole genome sequencing analysis of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), a globally prevalent condition caused by excess fat accumulation in the liver. The research aims to uncover...
- This federal Project Grant award of $544,963, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to investigate the role of the protein frataxin (FXN) in metabolic dysfunction-associated steatotic liver disease (MASLD). The research conducted under this award will examine whether FXN deficiency induces and whether restoration of FXN expression prevents...
- The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) awarded a $2,999,512 Project Grant under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to The University of Texas Southwestern Medical Center, doing business as Southwestern Medical School. This 4-year award, starting on September 1, 2025, will support research to investigate the regulation of mitochondrial health in mammalian livers, with a focus on understanding the...
- This federal Project Grant award of $737,034.00 was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The goal of this 5-year research project, with a start date of September 1, 2025, is to identify new regulatory inputs that control the biosynthesis of coenzyme A (CoA) in response to the metabolic state of cells and tissues, especially the kidney and liver. The...
This $551,696 Project Grant award, provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), aims to investigate the role of the cannabinoid 1 receptor (CB1R) in age-associated metabolic dysfunction-associated steatotic liver disease (MASLD). The research project, led by Oklahoma State University, seeks to determine how hepatic CB1R contributes to the exacerbation of MASLD in aging, particularly in relation to cellular senescence and gut dysbiosis. The award spans the period from September 12, 2025 to August 31, 2028 and supports this investigation into novel molecular mechanisms underlying the development and progression of MASLD, which affects approximately 80 million U.S. adults.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $551.7k | 9/11/25 |