Project Grant R15AI197231
- Federal Project Grant Award Summary Texas Tech University received a $150,220 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), effective August 1, 2025 through July 31, 2027. The award supports research on sickle cell disease (SCD) severity prediction using magnetic susceptibility analysis and hemoglobin content measurement in blood cells. The research project aims to develop an early...
- Federal Grant Award Summary Texas Tech University System received a $648,891 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 3, 2026, for research on "Population Dynamics at an Invasive Front: Aedes aegypti in the American Southwest." The project, extending through January 31, 2031, investigates the population structure and connectivity of Aedes aegypti...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded Texas Biomedical Research Institute $905,998 under the Allergy and Infectious Diseases Research program (CFDA 93.855) to evaluate the safety, immunogenicity, and efficacy of a novel attenuated Mycobacterium tuberculosis (MTB) vaccine candidate in the context of HIV co-infection. Commencing June 17, 2025, and extending through May 31, 2030, this project will leverage the institute's...
- Federal Project Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $422,355 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded July 23, 2025, with completion targeted for June 30, 2027. The grant funds mechanistic and structural studies examining the signaling histidine kinase GacS from Pseudomonas aeruginosa, a nosocomial...
- Federal Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The Methodist Hospital Research Institute a $2.71 million Project Grant under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 12, 2025, for research extending through May 31, 2029. This award supports the development and characterization of a novel generation of self-adjuvanted messenger RNA (mRNA) vaccines targeting Mycobacterium tuberculosis (MTB), the causative...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $437,541 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded February 2, 2026, with completion scheduled for January 31, 2028. The grant supports research focused on discovery and development of antisense therapeutics to treat Clostridioides difficile infection (CDI), a...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded the University of Texas Medical Branch at Galveston a $798,400 Project Grant on May 5, 2025, under the Allergy and Infectious Diseases Research program (CFDA 93.855). This five-year research initiative, extending through April 30, 2030, focuses on developing an innovative circular RNA vaccine platform targeting Andes virus (ANDV), a globally emerging hantavirus pathogen with...
- Federal Grant Award Summary Virginia Polytechnic Institute & State University (Virginia Tech) received a $452,769 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 11, 2025, to conduct research on the impact of BDGR-49 treatment on Venezuelan Equine Encephalitis Virus (VEEV) induced neurological sequelae. The research addresses a critical public health gap by...
- Federal Project Grant Award Summary Texas A&M University System Health Science Center received a $624,267 Project Grant award (CFDA 93.855, Allergy and Infectious Diseases Research) from the National Institute of Allergy and Infectious Diseases on August 11, 2025, with a completion date of July 31, 2030. The research initiative focuses on developing methods to understand how small molecule compounds penetrate the cellular envelope of gram-negative bacteria, particularly Acinetobacter...
- Federal Project Grant Award Summary The National Institute of Allergy and Infectious Diseases (NIAID) awarded The University of Texas Southwestern Medical Center a Project Grant of $3,278,392 under the Allergy and Infectious Diseases Research program (CFDA 93.855) on August 21, 2025, for research extending through July 31, 2029. This award supports biomedical research investigating the role of ubiquitin ligases and deubiquitinases in host defense mechanisms against Mycobacterium tuberculosis...
Texas Tech University received a $587,528 Project Grant from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) to assess the tolerability and versatility of the SpyTag003/SpyCatcher003 bio-conjugation system for vaccine development. The three-year award, effective April 1, 2026 through March 31, 2029, supports research aimed at displaying diverse protein antigens on the surface of bacteriophage virus-like particles (VLPs) across four bacterial phage platforms: MS2, PP7, AP205, and Q. The research addresses a critical limitation in peptide and protein antigen vaccine design by developing an alternative bio-conjugation approach to overcome the constraints of existing genetic insertion and chemical conjugation methods. The deliverables include comprehensive evaluation of the new SpyTag003/SpyCatcher003 system's versatility and effectiveness in creating multivalent, highly immunogenic vaccine candidates using bacteriophage VLPs. This work is conducted at Texas Tech University's facility in Amarillo, Texas and is expected to generate scientific knowledge and methodological advances supporting improved vaccine development strategies for infectious diseases.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $587.5k | 3/30/26 |