Project Grant R03HD111034
- The University of Michigan received a $280,260 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research (CFDA 93.865) program. The grant, awarded on December 1, 2024, with a completion date of March 13, 2027, aims to improve the design and functionality of ankle-foot orthoses (AFOs) used to address foot drop and gait issues. The project will develop a "Decoupled Energy Storage and Return Variable...
- This federal Project Grant award of $1,875,712 from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420) supports the "The Baby Duchenne Study: Characterizing Developmental and Clinical Outcomes in the First 3 Years in Children with Duchenne Muscular Dystrophy" research project. The grant, awarded to the University of Rochester on September 30, 2025, will fund a comprehensive study to investigate developmental and clinical outcomes in young...
- This federal Project Grant award of $671,240 from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846) supports research to develop enhanced dystrophin gene therapies for Duchenne muscular dystrophy (DMD). The University of Washington will conduct this research from January 2025 through December 2029. The project aims to design and test micro-, mini-, and full-length dystrophin gene...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $686,880 Project Grant under the Child Health and Human Development Extramural Research program (CFDA 93.865) to Marquette University. The grant, titled "Advancing Functional Assessment of Pediatric Flatfoot Using Weightbearing CT", will fund a 5-year research project to comprehensively study the 3D structure and function of pediatric planus (flatfoot) deformities using emerging...
- This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $692,292.00 to the Children's Research Institute in Washington, D.C. to conduct research aimed at understanding the regulation of pediatric regenerative myogenesis and its implications for muscle disease. The key products and services to be delivered under this 5-year award...
- This Project Grant award of $224,580.00, provided by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research (CFDA 93.865) federal grant program, supports research to investigate the role of muscle spindles in the control of balance and movement. The research, conducted by Emory University, aims to combine computational modeling of muscle spindle dynamics with direct recordings of muscle spindle activity and fascicle...
- This federal Project Grant award, with $405,341 in funding from the Defense Health Agency's Military Medical Research and Development program (CFDA 12.420), supports research by the Children's Research Institute to explore the use of pro-resolution and restorative pharmacology approaches for the treatment of Duchenne muscular dystrophy (DMD). The 3-year project, running from August 1, 2025 to July 31, 2028, aims to develop innovative medical solutions to address this critical health challenge...
- The University of Florida was awarded a $599,496 project grant by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research federal grant program (CFDA 93.846). The objective of this 5-year project, with a performance period from September 15, 2025 to August 31, 2030, is to evaluate the potential of magnetic resonance (MR) measures of bioenergetics and microvascular function to track disease progression and...
- The Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) awarded a $302,500 Project Grant to Myogene Bio LLC, a woman-owned small business in San Diego, California. The grant, provided under NICHD's Child Health and Human Development Extramural Research program (CFDA 93.865), supports research to assess the use of a restored dystrophin protein as a biomarker for evaluating the efficacy of a gene editing therapy for Duchenne muscular dystrophy (DMD). The...
- The University of Florida Division of Sponsored Research received a $536,800 Project Grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) under the Arthritis, Musculoskeletal and Skin Diseases Research program (CFDA 93.846). The grant will fund a 3-year exploratory clinical trial to investigate the potential of the drug tadalafil, combined with structured exercise training, to improve muscle pathophysiology and function in individuals with Duchenne...
This Project Grant award from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), provides $305,000.00 to the University of Florida to evaluate the mechanisms driving ankle contractures in individuals with Duchenne muscular dystrophy (DMD). The research aims to quantify the impact of muscle weakness and degeneration on ankle joint range of motion, as well as assess the tissue adaptations such as changes in plantarflexor muscle length, Achilles tendon length, and muscle-tendon stiffness that occur alongside the loss of joint range of motion. The data collected from this 2-year project will help inform more evidence-based interventions to prevent or slow the development of ankle contractures in DMD patients.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $305.0k | 7/8/24 |