Project Grant R03DE034789
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research awarded a $521,362 Project Grant to The Johns Hopkins University beginning August 12, 2025, and concluding August 11, 2027, under the Oral Diseases and Disorders Research program (CFDA 93.121). The award supports fundamental research aimed at decoding neuroimmune interactions to enhance craniofacial bone healing. The research will employ quantitative light-sheet microscopy (QLSM) and single-cell RNA sequencing...
- Federal Grant Award Summary The Oklahoma Medical Research Foundation (OMRF) received a $468,875 Project Grant award from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective September 19, 2025, through September 18, 2027. The award supports a two-year research initiative investigating age- and sex-related immune mechanisms involved in salivary gland pathology associated with Sjögren's Disease (SJD), a...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded $104,506 on March 5, 2025, under the Oral Diseases and Disorders Research program (CFDA 93.121) to support a research project titled "Single-Cell Profiling of Follistatin Within the Tumor Landscape of Oral Squamous Cell Carcinoma." The Research Foundation for the State University of New York, serving as the fiscal and administrative agent, will oversee execution of this...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded the University of Southern California a $688,679 Project Grant effective August 1, 2025, through April 30, 2030, under the Oral Diseases and Disorders Research program (CFDA 93.121). This award funds an innovative research initiative to comprehensively map transcriptomes and lineage relationships in craniofacial tissues through a cross-disciplinary collaboration between craniofacial...
- Federal Project Grant Award Summary Old Dominion University Research Foundation (Odurf) received a $583,826 Project Grant award from the National Institute of Dental and Craniofacial Research under the Oral Diseases and Disorders Research program (CFDA 93.121) on August 14, 2025, with completion targeted for August 13, 2028. The award supports research focused on pre-vascularization of an integrated three-dimensional human osteo-mucosal (bone and soft tissue) model, building upon the awardee's...
- Federal Grant Award Summary Oregon Health & Science University (OHSU) received a $704,206 Project Grant from the National Institute of Dental and Craniofacial Research (NIDCR) under the Oral Diseases and Disorders Research program (CFDA 93.121), effective July 1, 2025, through March 31, 2030. The award supports the development and validation of an organ-on-a-chip model that replicates the tumor-bone interface in oral squamous cell carcinoma (OSCC), specifically examining how cancer cells...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research awarded The Research Foundation for the State University of New York a Project Grant of $320,200 (awarded July 15, 2025, with completion anticipated July 14, 2027) under the Oral Diseases and Disorders Research program (CFDA 93.121). This award funds research to define the gene regulatory mechanisms of MLL4 (KMT2D), an epigenetic coactivator, in tooth enamel development and amelogenesis. The research...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The University of Iowa a Project Grant valued at $503,648 under the Oral Diseases and Disorders Research program (CFDA 93.121), effective June 13, 2025, with completion targeted for March 31, 2030. This research grant supports a comprehensive investigation into the transcriptional mechanisms governing mandibular patterning during oral and craniofacial development. The project examines how...
- Federal Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded The Research Foundation for the State University of New York $870,334 under the Oral Diseases and Disorders Research program (CFDA 93.121) for a two-year project grant running from August 1, 2025, through July 31, 2027. The project focuses on developing an early tooth organoid using human induced pluripotent stem cells (iPSCs) to address gaps in understanding tooth development and disease...
- Federal Project Grant Award Summary The National Institute of Dental and Craniofacial Research (NIDCR) awarded University of California, Los Angeles $315,000 through the Oral Diseases and Disorders Research program (CFDA 93.121) to conduct basic and translational research on cranial suture development and disease. The project, awarded July 15, 2025, with completion targeted for July 14, 2027, investigates the distinct roles of neural crest cell populations in cranial suture physiology and...
The National Institute of Dental and Craniofacial Research (NIDCR) awarded Oklahoma Medical Research Foundation (OMRF) a Project Grant of $341,000 under the Oral Diseases and Disorders Research program (CFDA 93.121) to conduct basic research on platelet-derived growth factor receptor beta (PDGFRβ)-mediated skeletal-vascular crosstalk in calvarial bone marrow development. The research, spanning from February 15, 2026 to February 14, 2028, will characterize how PDGFRβ signaling in skeletal cells promotes bone marrow formation through an angiogenesis-directed mechanism in calvarial (skull) bones. This fundamental research initiative leverages OMRF's extensive laboratory capabilities and animal research infrastructure to investigate the cellular communication between skeletal cells, vascular endothelial cells, and hematopoietic cells that regulate bone marrow niche formation—findings with potential implications for understanding bone marrow development and identifying novel therapeutic targets for fibrosis, cardiovascular disease, and cancer. The award supports translational research that advances basic knowledge in craniofacial health and disease, consistent with NIDCR's mission to translate research findings into prevention and treatment strategies. OMRF will conduct this research at its Oklahoma City facility, where the foundation's 50+ research laboratories and 400+ staff members specialize in biomedical research across multiple scientific disciplines, providing the necessary technical expertise and animal husbandry services required for this developmental biology investigation.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $341.0k | 2/13/26 |