Project Grant R03DA064474
Award Date 9/1/25
Completion Date 8/31/27
Dollars Obligated $357K
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
Roxbury, MA 02118, USA
Similar Awards
- This federal Project Grant award of $1,210,300 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports the development of novel polyvalent HIV vaccines to protect people who inject drugs (PWID) against intravenous HIV transmission. The project aims to create a vaccine that can elicit high levels of immune responses to rapidly clear multiple HIV strains that may be transmitted through needle use. The grant was awarded to Beth...
- This federal Project Grant award for $711,993.00, provided by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support research to examine the effects of Mycobacterium tuberculosis (MTB) disease on HIV-1 pathogenesis in people living with HIV (PWH). The research aims to assess how MTB disease influences the development of broadly neutralizing HIV-1 antibodies, the emergence of NAb-resistant viral...
- This federal Project Grant award of $240,108 from the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279) aims to elucidate the corticostriatal and neuroimmune mechanisms underlying HIV-induced dysregulation of reward seeking. The award to Drexel University will support research to identify novel treatment targets for individuals with co-occurring cocaine use disorders and HIV. The project will leverage animal models to investigate how HIV...
- The federal Project Grant award of $1,465,275.00 from the National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), supports research to investigate the role of HIV proteins in psychostimulant abuse, specifically focused on understanding how HIV and HIV viral proteins alter the molecular actions and behavioral expressions of amphetamine. The project aims to elucidate the mechanisms by which HIV infection and HIV proteins, such as Tat and gp120,...
- The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $558,668 Project Grant under the Drug Use and Addiction Research Programs (CFDA 93.279) to the Massachusetts Institute of Technology (MIT) for the project "Integration and Validation of Single-Cell Neuronal and Immune Molecular Responses in SUD and HIV". The project aims to uncover the genetic and molecular mechanisms driving the interactions between HIV, neuropsychiatric, and...
- This federal Project Grant award, valued at $563,742.00, was provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279). The grant supports research to investigate the impact of HIV infection and cocaine use on lipid metabolism in microglia, a type of brain cell, and the role this plays in the development of neurological symptoms associated with HIV (referred to as NeuroHIV). Key research activities include: Examining how HIV proteins...
- This federal Project Grant award, provided by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), totaling $1,742,971 and commencing on April 15, 2025, aims to investigate the role of cannabinoids in modulating cocaine-induced inflammasome activation and epigenetic regulation in the intestine and brain during HIV/SIV infection. The primary objectives are to: 1) examine the impact of cocaine and HIV/SIV on inflammasome activation and its...
- The National Institute on Drug Abuse (NIDA), under the Drug Use and Addiction Research Programs (CFDA 93.279), awarded a $687,416 Project Grant to the J. David Gladstone Institutes in San Francisco, California. The grant is for a research project titled "Targeted Small Molecule Recruitment to Suppress the HIV Transcriptionally Active Reservoir" and runs from May 15, 2025 to March 31, 2030. The key objectives of this research project are to develop therapeutically effective...
- This Project Grant award, funded by the National Institute on Drug Abuse (NIDA) under the Drug Use and Addiction Research Programs (CFDA 93.279), aims to investigate the effects of opioids on HIV transcription and latency. The $234,000 award to Georgetown University will support research using a novel dual fluorescent and bioluminescent virus called EcoHIV NL4-3 Dual Red to visualize active HIV proviral transcription in microglia and astrocytes. The study will examine the mechanisms by which...
- This Project Grant award of $1,573,958 from the National Institute on Drug Abuse (NIDA), part of the Drug Use and Addiction Research Programs (CFDA 93.279), is focused on identifying individuals who are viremic and/or have substance use disorder (SUD) to engage them for early intervention. The project will implement routine SUD screening using the NIDA Quick Screen and a social network intervention to find individuals who are viremic, have SUD, or both, and link them to harm reduction and HIV...