Project Grant R03CA300834

Award Date 6/20/25
Completion Date 5/31/27
Dollars Obligated $159K
Federal Grant Program
93.395
Assistance Type
Project Grant
Place of Performance
Georgia, USA
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This Project Grant award from the National Cancer Institute (CFDA 93.395 - Cancer Treatment Research) provides $158,899 to Emory University to develop an innovative platform for conformal flash proton therapy to treat central lung cancer. The key products and services to be delivered include:

  1. Establishing a Simultaneous Intensity Energy Modulation and Compensation (SIEMAC) optimization platform to inversely solve the variables (intensity and energy) of the Integrated Physical Optimization (IPO) objectives for conformal flash proton therapy. This will compare SIEMAC-optimized plans to intensity-modulated proton therapy (IMPT) plans for 10 central lung cancer patients.

  2. Developing a quality assurance (QA) platform to validate Monte Carlo-calculated ultra-high dose rates and linear energy transfer for the SIEMAC-optimized conformal flash proton therapy plans. This will involve 3D printing example passive energy modulation filters and using advanced detector systems to measure key parameters.

The award period is from Jun 20, 2025 to May 31, 2027.

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