This Project Grant award of $159,500.00 from the National Cancer Institute (NCI), under the federal Cancer Cause and Prevention Research program (CFDA 93.393), supports research to investigate the role of the Signal Transducer and Activator of Transcription (STAT) protein in the initiation of heterochromatin, a tightly packed form of DNA essential for chromosomal compaction, transcriptional silencing, genome stability, and tumor suppression. The project, led by researchers at the University of California, San Diego (UCSD), aims to employ genomic, genetic, and biochemical tools to better understand the molecular mechanisms underlying heterochromatin establishment, which could lead to novel cancer therapeutics through targeted epigenetic gene silencing. The award period runs from July 1, 2025 to June 30, 2027.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $159.5k | 6/19/25 |