Project Grant R01NS148504
- Federal Grant Award Summary The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. received a $1.11 million Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded March 5, 2026, with a completion date of December 31, 2030. The award funds research on neural plasticity and myelin dynamics following unilateral denervation...
- Federal Grant Award Summary The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. received a $856,523 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to conduct research on neurovascular and cognitive recovery from the spectrum of traumatic brain injuries (TBIs) through high-low therapy. Awarded on September 30, 2025, with an ultimate completion date of September 29, 2028, this three-year...
- Federal Grant Award Summary The Defense Health Agency awarded a $4.63 million Project Grant under the Military Medical Research and Development program (CFDA 12.420) to The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc., effective August 1, 2025, through July 31, 2028. The award funds research to elucidate the role of the neurovascular unit and associated structural and functional neurological sequelae following exposure to repeated blast events. This three-year...
- Summary of Federal Project Grant Award The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. received a $488,086 Project Grant from the Defense Health Agency (DHA) under the Military Medical Research and Development program (CFDA 12.420) to conduct research on biomarker signatures of post-traumatic epileptogenesis and its treatments. The award, effective May 1, 2025 through April 30, 2027, supports advanced biomedical research aimed at identifying diagnostic and...
- Federal Project Grant Award Summary Massachusetts General Hospital's Research Management Division received a $322,382 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded June 1, 2026, with a completion date of March 31, 2031. The award funds basic neuroscience research investigating the cell-specific mechanisms of interleukin-1 receptor 1...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $654,218 Project Grant to the University of Maryland, Baltimore on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The five-year research initiative, scheduled for completion on July 31, 2030, investigates the mechanisms and intervention strategies of cyclic GMP-AMP synthase (cGAS) signaling in brain trauma-induced...
- Federal Grant Award Summary The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. received a $749,822 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for the project "Beyond Repair: Transformative Multistaged Treatment for Composite Tissue Injuries." The award, effective September 30, 2025, with an ultimate completion date of September 29, 2028, supports research and development activities...
- Federal Grant Award Summary The University of South Florida received a $568,920 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective April 17, 2026, with completion targeted for March 31, 2031. The award funds research investigating how traumatic brain injury (TBI)-induced dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis affects...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The Ohio State University a Project Grant totaling $202,599 effective September 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). This research initiative investigates the role of NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) in chronic inflammation, microglia priming, and neuropsychiatric...
- Federal Grant Award Summary The University of Kentucky Research Foundation received a $192,500 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded February 1, 2026, with completion targeted for January 31, 2028. The award funds a two-year research project investigating the mechanisms by which repetitive mild traumatic brain injury (TBI) combined...
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. received a $372,880 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) awarded July 15, 2026, with completion targeted for May 31, 2031. This award supports basic neuroscience research investigating lateral habenula circuit dysfunction in mild traumatic brain injury (mTBI), specifically examining how mTBI-induced changes in cortico-habenular microcircuits contribute to treatment-resistant neuropsychiatric disorders including depression, anxiety, and post-traumatic stress disorder. The research deliverables encompass mechanistic investigations using a validated repetitive mTBI mouse model, employing advanced methodologies including viral strategies, optogenetics, electrophysiology, in vitro calcium imaging, astrocyte modulation tools, and chemogenetics to determine the synaptic and behavioral effects of mTBI on medial prefrontal cortical projections to the lateral habenula. The project will pursue two primary research aims examining both the direct impacts of mTBI on specific cortico-habenular circuits and the role of astrocyte-neuronal interactions in mood dysregulation, with analysis conducted in both male and female mice to ensure sex-balanced research outcomes. Findings are intended to establish causal links between circuit dysfunction and motivational deficits, potentially identifying novel therapeutic targets for mTBI-related neuropsychiatric complications.Federal Project Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $372.9k | 7/7/26 |