Project Grant R01NS147347
- The National Institute of Neurological Disorders and Stroke awarded the University of Florida $592,967 on August 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to optimize therapeutic acute intermittent hypoxia (TAIH) as a treatment for improving breathing and motor function after cervical spinal cord injury. The research investigates temporal variation in TAIH efficacy across injury phases—sub-acute, early-chronic, and...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $234,750 on January 26, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate neuromodulation of somato-sympathetic postganglionic activity after spinal cord injury. The research develops animal models incorporating clinically analogous epidural spinal cord stimulation to understand how neuromodulation can restore autonomic function...
- The National Institute of Neurological Disorders and Stroke awarded Mayo Clinic $622,784 on July 21, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate acute and chronic repercussions of spinal cord stimulation following spinal cord injury. The research quantifies blood pressure instability after spinal cord injury, which interrupts descending autonomic regulatory signals and causes loss of consciousness, stroke,...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $150,342 to the University of Washington on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds investigation of how long-term, closed-loop, epidural spinal cord stimulation affects neuropathic pain symptoms in rats with cervical spinal cord injury. The...
- The National Institute of Neurological Disorders and Stroke awarded Drexel University $149,190 on July 14, 2026, under CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) to conduct research on transcutaneous spinal cord stimulation and its mechanisms for reducing spasticity following spinal cord injury. The research investigates whether transcutaneous spinal cord stimulation improves spasticity after spinal cord injury by upregulating KCC2, a chloride...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $408,750 project grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded on August 1, 2025, with completion targeted for July 31, 2027. This award funds investigator-initiated research examining the mechanisms of swallowing dysfunction in chronic cervical spinal cord injury...
- The National Institute of Neurological Disorders and Stroke awarded Florida International University $471,698 on May 13, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of perivascular fibroblasts in secondary spinal cord injury. The research focuses on peptidase inhibitor 16 (PI16) as a novel therapeutic target for neuroprotection after spinal cord injury. Preliminary studies indicate that activation of...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $660,613 to The Trustees of Columbia University in the City of New York on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research on spinal cord stimulation as a combination therapy to enhance motor function in spinal muscular atrophy (SMA). The research...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $470,293 to The Research Foundation For The State University of New York (SUNY at Binghamton) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, effective July 1, 2025, through June 30, 2027. This Project Grant funds research aimed at identifying and characterizing the electrophysiological features of spinal motor neurons during...
- The National Institute of Neurological Disorders and Stroke (part of the Department of Health and Human Services National Institutes of Health) awarded $367,075 to the University of Newcastle Upon Tyne on September 5, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853, Project Grant R01NS150256). The award funds research into paired stimulation plasticity for motor recovery following cervical spinal cord injury, with the goal of...
The National Institute of Neurological Disorders and Stroke awarded the University of Florida $605,411 on August 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate mechanisms of cervical epidural stimulation for respiratory recovery following spinal cord injury. The project focuses on closed-loop epidural stimulation as a neuromodulation strategy to restore diaphragm activation and promote respiratory motor plasticity in cervical spinal cord injury models. Using cervical hemisection and contusion rat models, the research will determine optimal stimulation paradigms and identify the anatomical substrates necessary to increase diaphragm motor output during acute neuromodulation and after long-term stimulation in both acute and chronic injury phases. The underlying hypothesis proposes that closed-loop epidural stimulation restores diaphragm activation via a mechanism requiring phrenic afferents, with the aim of informing human clinical applications for patients requiring ventilator support following cervical spinal cord injury. Performance occurs at the University of Florida in Gainesville, Florida, with the award period running through July 31, 2031. The University of Florida Division of Sponsored Research serves as the administering entity for the prime recipient.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $605.4k | 8/17/26 |