Project Grant R01NS146942
- The National Institute of Neurological Disorders and Stroke awarded the University of Florida $605,411 on August 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate mechanisms of cervical epidural stimulation for respiratory recovery following spinal cord injury. The project focuses on closed-loop epidural stimulation as a neuromodulation strategy to restore diaphragm activation and promote respiratory motor...
- The National Institute of Neurological Disorders and Stroke awarded Florida International University $471,698 on May 13, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate the role of perivascular fibroblasts in secondary spinal cord injury. The research focuses on peptidase inhibitor 16 (PI16) as a novel therapeutic target for neuroprotection after spinal cord injury. Preliminary studies indicate that activation of...
- The National Institute of Neurological Disorders and Stroke awarded the University of South Florida $568,920 on April 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate how traumatic brain injury–induced hypothalamic-pituitary-adrenal (HPA) axis dysregulation affects neuroplasticity and rehabilitation efficacy, with focus on sex differences. The project, titled "Aligning Circuit-Directed Rehabilitation with...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Miami $368,695 on June 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop small-molecule inhibitors of arginyltransferase 1 (ATE1) for treatment of spinal cord injury. The recipient will establish and optimize a dual-fluorescence, cell-based reporter platform to monitor ATE1 activity in live cells with high sensitivity and...
- The National Heart, Lung, and Blood Institute awarded the University of Florida $159,560 on December 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to support postdoctoral research training on ENAMPT targeting to modulate brain and lung injury following traumatic brain injury exposure. The award funds a postdoctoral fellow's research exploring the role of extracellular nicotinamide phosphoribosyltransferase (eNAMPT) in mediating traumatic brain injury (TBI)-mediated...
- The National Institute of Neurological Disorders and Stroke awarded a $168,714 cooperative agreement to the University of Florida on August 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds the University of Florida Early Research Program for Neurology and Neurosurgery Residents, which develops a comprehensive early research pipeline engaging neurology and neurosurgery residents in research from the start of...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $408,750 project grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), awarded on August 1, 2025, with completion targeted for July 31, 2027. This award funds investigator-initiated research examining the mechanisms of swallowing dysfunction in chronic cervical spinal cord injury...
- Federal Project Grant Award Summary The University of Florida's Division of Sponsored Research received a $482,708 Project Grant award from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) to support research combining therapeutic acute intermittent hypoxia and respiratory-triggered diaphragm pacing to restore breathing function in chronic cervical spinal cord injury. The three-year project, which commenced September 30, 2025 and concludes...
- The National Institute of Neurological Disorders and Stroke awarded the University of Florida $611,097 on July 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to establish and operate the START (Subarachnoid Hemorrhage Translational Advanced Research Pre-Trial) Network, a multi-site preclinical testing framework designed to bridge the translational gap between animal models and human clinical trials. The START Network will...
- The National Institute of Neurological Disorders and Stroke awarded the University of Miami $581,794 on September 7, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research into inflammasome activation and its role in the foreign body response triggered by chronically implanted microelectrodes in neural tissue. Microelectrode implants enable neuroprosthetic and neuromodulation technologies for patients with...
The National Institute of Neurological Disorders and Stroke awarded the University of Florida $592,967 on August 17, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to optimize therapeutic acute intermittent hypoxia (TAIH) as a treatment for improving breathing and motor function after cervical spinal cord injury. The research investigates temporal variation in TAIH efficacy across injury phases—sub-acute, early-chronic, and late-chronic—and tests the hypothesis that shifting balance between serotonin-driven and adenosine-driven plasticity mechanisms in spared neural pathways explains why TAIH improves breathing in rats with sub-acute cervical hemisection and late-chronic injury but shows minimal impact during the early-chronic phase. The project will test specific TAIH protocols optimized to favor adenosine-driven plasticity in sub-acute injury and serotonin-driven plasticity in late-chronic injury. The award carries a period of performance from August 17, 2026, through July 31, 2031, with place of performance in Gainesville, Florida. The University of Florida Division of Sponsored Research administers the award as the recipient institution.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $593.0k | 8/17/26 |