Project Grant R01NS144236
- This federal Project Grant award, valued at $147,486, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The purpose of this award is to investigate the function of a ciliary protein in neural development, with a focus on uncovering novel molecular mechanisms involved in synapse formation that may be relevant to neurological disorders. Using C. elegans as...
- This $2,503,949 Project Grant awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at Rockefeller University aimed at discovering therapeutic targets for neurological diseases. The project utilizes new techniques and concepts to study the fundamental mechanisms of brain disorders, focusing on how differences in cell-specific RNA regulation contribute to...
- This $132,377 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support research by the University of California, Los Angeles (UCLA) to identify the cells and circuits driving stimulus-independent activity throughout the developing Drosophila (fruit fly) brain. The research aims to understand how coordinated, spontaneous neural activity across...
- This federal Project Grant award, ID R35NS137247, was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award totaling $1,174,913.00 supports research to understand the fundamental mechanisms of homeostatic plasticity, a compensatory process that stabilizes neural function, and its potential links to neurodevelopmental disorders such as autism and...
- This $270,434 federal Project Grant award, funded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the mechanistic link between spatiotemporal regulation of mRNA and neuronal remodeling during morphogenesis. The principal investigator will use Drosophila mushroom body and dendritic arborization neurons as models to study the...
- This federal Project Grant award, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), will support research to characterize a genetic mouse model for a gene implicated in neurodevelopmental disorders including autism, intellectual disability, and schizophrenia. The $742,484 award, with a project period from January 13, 2025 to October 31, 2029, will fund experiments to obtain multiome single nucleus RNA-sequencing,...
- This federal Project Grant award of $236,250 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research to elucidate how alternative splicing of the DPF2 subunit of the chromatin remodeling BAF complex regulates epigenetic programs and neuronal maturation during brain development. The research aims to utilize CRISPR/Cas9-edited embryonic stem cell lines and mouse...
- This federal Project Grant award of $390,000.00 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to investigate the role of dysregulated eIF4E-mediated translational control in the pathogenesis of Focal Cortical Dysplasia Type II (FCDII), a neurodevelopmental disorder that causes focal cortical malformations and drug-resistant epilepsy. The...
- This $539,999 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, aims to investigate the role of the NKX2.1 homeobox transcription factor in nervous system development. The research, to be conducted by Kennesaw State University, will utilize the nematode Caenorhabditis elegans as a model organism to better understand how NKX2.1 and related...
- This federal Project Grant award of $195,889 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award will fund research at Duke University to investigate the role of human-specific non-coding sequences within introns in regulating RNA splicing during cortical development and their relationship to neurological diseases like autism. Specifically, the...
This $512,423 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) supports research at the University of Utah to investigate the role of the IGF2BP family of RNA binding proteins in brain development and their relationship to neurodevelopmental disorders. The research aims to elucidate how the fly orthologue IMP regulates the mRNA target SAP47/SYAP1, which is a known autism spectrum disorder risk factor, and how disruption of this pathway leads to microcephaly and improper brain wiring. The project will leverage fly and mouse models as well as human gene variants to study these mechanisms from August 2025 through July 2030.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $512.4k | 7/31/25 |