Project Grant R01NS143960
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Colorado-Denver a Project Grant totaling $427,712 on March 2, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The award supports a two-year research initiative (through February 29, 2028) focused on developing machine learning-based methods to identify and classify disease-associated B cell...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $535,124 Project Grant to The Regents of the University of Colorado (University of Colorado-Denver) on June 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award supports research investigating neural circuits for disinhibition in the cerebellum, with a project completion date of March 31, 2031. The research aims...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded a Project Grant of $152,300 to The Regents of The University of Colorado, doing business as University of Colorado-Denver, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award, obligated on May 1, 2026, with a completion date of June 30, 2028, supports fundamental neuroscience research investigating the role of...
- Federal Project Grant Award Summary Colorado State University received a $496,279 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), effective March 1, 2026, through November 30, 2030. The award funds fundamental neuroscience research investigating cholinergic synaptic homeostasis (HSP)—the compensatory mechanisms neurons employ to maintain...
- Federal Grant Award Summary Vanderbilt University received a $103,449 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded December 1, 2025, with a completion date of May 31, 2027. The research project, titled "Patient-Centered Neurological Evaluation of Functional MRI Outcomes in Multiple Sclerosis," focuses on developing and...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $115,265 to The Regents of the University of Colorado (University of Colorado-Denver) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program on November 27, 2025. The project, titled "Impact of Developmental Glutamatergic Signaling on Oligodendrocyte Differentiation," will be conducted through October 31, 2027, and focuses on...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded $608,679 to the University of South Florida on August 1, 2025, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to support a five-year research project through July 31, 2030. The research focuses on elucidating the molecular mechanisms of claudin-5 regulation during neuroinflammation, specifically investigating the roles of...
- Federal Project Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded Cleveland Clinic Lerner College of Medicine of Case Western Reserve University a Project Grant totaling $544,568 (awarded February 11, 2026, with completion targeted for December 31, 2030) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating the pathogenesis of permanent neurological...
- Federal Grant Award Summary The National Institute of Neurological Disorders and Stroke (NINDS) awarded The University of Kentucky Research Foundation a Project Grant of $662,969 on June 19, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. This award supports research to improve disease-modifying therapy (DMT) uptake among patients with multiple sclerosis (MS), with research performance occurring through May 31, 2030. The project...
- Federal Grant Award Summary The University of Colorado-Denver received a $250,401 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), awarded July 23, 2025, with completion targeted for November 30, 2026. This research initiative investigates the mechanisms by which amyloid-beta (Aβ) peptide disrupts synaptic nanoarchitecture in Alzheimer's disease...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded the University of Colorado-Denver a $575,655 Project Grant on June 16, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The award funds research investigating paired-vagus nerve stimulation (paired-VNS) as a therapeutic approach to promote remyelination and motor functional recovery in demyelinating diseases, specifically multiple sclerosis (MS). The research will examine how paired-VNS influences myelin repair mechanisms, including oligodendrogenesis and sheath replacement specificity, with the objective of establishing evidence supporting future clinical investigations of VNS therapy in MS patients. Research activities will continue through March 31, 2031, and are being conducted at the University of Colorado-Denver's Aurora, Colorado facility. This project addresses a significant public health need, as MS affects approximately 1 million individuals in the United States and currently available disease-modifying therapies do not prevent the accumulation of disability or cognitive impairments associated with myelin loss. The proposed research builds on preliminary data demonstrating that paired-VNS promotes remyelination, restores myelin patterns, and improves functional recovery, with anticipated outcomes providing critical foundational evidence for translating this bioelectric intervention to clinical applications.Federal Grant Award Summary
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $575.7k | 6/15/26 |