Project Grant R01NS140465
Award Date
7/15/25
Completion Date
6/30/30
Dollars Obligated
$573K
Federal Agency
National Institute of Neurological Disorders and Stroke
Federal Grant Program
93.853
Assistance Type
Project Grant
Place of Performance
Palo Alto, CA 94304, USA
Similar Awards
This Project Grant award of $598,952 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support the development of a novel human stem cell-derived multi-cellular model to study the developmental processes underlying spinal cord midline crossing of axons. The awardee, The Leland Stanford Junior University, will generate and functionally characterize organoids...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $190,485 to Trustees of Indiana University, doing business as Indiana University Indianapolis, to conduct research into the molecular mechanisms underlying differentiation failure in neuroepithelial stem cells with NF2 gene mutations. The research aims to identify the cellular...
This Project Grant award of $385,500 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports the development of a novel inducible and multiplexed dual gene regulation CRISPR system to study neuronal activity and regeneration. The award will fund research at The Leland Stanford Junior University (Stanford University) to engineer a system capable of simultaneous...
This federal Project Grant award of $2,307,075, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under CFDA 93.853 Extramural Research Programs in the Neurosciences and Neurological Disorders, supports an ambitious research program at Stanford University focused on defining novel mechanisms of human neurodegenerative diseases and translating those findings into new therapeutic strategies. The key objectives of this grant include: 1) Conducting genome-wide...
This $251,370 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program supports research to understand the role of the transcription factor BMAL1 in regulating oligodendrocyte precursor cell (OPC) differentiation and myelination. The research aims to characterize BMAL1's impact on OPC transcriptional regulation, evaluate methods to restore OPC...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $877,001 to The Washington University to conduct research on modeling neurofibromatosis-1 (NF1) disease heterogeneity. The goal is to mechanistically define the cellular and molecular interdependencies underlying NF1-associated low-grade gliomas and neurodevelopmental deficits, and...
This $195,896 Project Grant, awarded by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to define the circuit connectivity between glioblastoma, a fatal brain cancer, and diverse neuronal populations in the mouse brain. The research aims to elucidate the role of cholinergic neuromodulatory inputs in regulating glioma progression, with the goal of...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $645,391 to The Trustees of Columbia University in the City of New York to conduct research on the effects of re-expressing embryonic motor neuron selector transcription factors in mouse models of amyotrophic lateral sclerosis (ALS) and in ALS motor neurons derived from induced...
This $424,875.00 Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund a comprehensive study of gene transcription patterns in diverse classes of neurons that connect the brain to the spinal cord after spinal cord injury in a mouse model. The research team at Marquette University will use single-cell sequencing technologies to profile...
This $210,600 federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program will fund research to investigate how Wnt signaling mediates the formation of repair cells from Schwann cells in the peripheral nervous system. The primary goals are to 1) provide functional tests of the role of Wnt receptors and ligands in controlling repair cell...