This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders federal grant program (CFDA 93.853), will provide $123,616.00 to investigate the role of the blood-brain barrier in the trafficking of prenatal liver-derived immune cells into the brain. The research aims to elucidate the cellular and molecular development of the blood-brain barrier and its impact on cellular...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $770,502 to The Regents of the University of California, San Francisco to conduct research on a model of cerebral small vessel disease. The goal is to understand the molecular mechanisms by which collagen IV regulates TGF-beta signaling, perform intravital imaging of the...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $1,341,874 project grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Regents of the University of California, San Francisco (UCSF). The grant supports research focused on elucidating the molecular mechanisms that control dendrite development, as well as studying mechanosensation and regeneration in Drosophila dendritic arborization (DA) neurons. Key...
The National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health, awarded a $2,272,234 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to the University of Rochester. The goal of this 5-year award is to determine the role of monocyte delta-like 4 (DLL4) in cerebral small vessel disease and its impact on cognition in people with HIV. The research aims to investigate how monocyte...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $129,454 to the University of Maryland, Baltimore to study the role of the SUR1-TRPM4 channel in chronic seizure susceptibility. The research aims to define how neuronal expression of this channel contributes to hyperexcitability and seizure activity, with the goal of...
The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $537,508 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program to The Research Foundation For The State University Of New York, doing business as Stony Brook University. This 5-year award (12/1/2024 - 11/30/2029) supports research to elucidate the role of endogenously formed zinc protoporphyrin (ZnPP) in brain damage following intracerebral hemorrhage...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to investigate how mechanosensation at the choroid plexus contributes to intracranial pressure (ICP) regulation in health and disease. The $296,108 award to the Scripps Research Institute will fund experiments using electrophysiology, calcium imaging, and ICP...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under CFDA Program 93.853 - Extramural Research Programs in the Neurosciences and Neurological Disorders, provides $9,631,026 to Northwestern University to conduct a comprehensive analysis of the impact of atherosclerosis on the brain's microvasculature in the context of Alzheimer's disease (AD). The research aims to deepen the understanding of the relationship between vascular health and...
This Project Grant award for $2,398,590.00, provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, will support research to investigate the role of brain microcirculation and capillary endothelial cell energetics in the development of vascular cognitive impairment and dementia (VCID) observed in Alzheimer's disease (AD) and AD-related dementias. The...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $171,728 to The Washington University to investigate the role of cerebrospinal fluid (CSF) flow in regulating the migration of bone marrow-derived myeloid cells to the central nervous system (CNS) after spinal cord injury. The research aims to determine if disruptions in CSF flow...