The University of South Carolina (USC) was awarded a $559,820 Project Grant from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) grant program. The objective of this 5-year grant is to characterize the biomechanical response of the human brain during high-severity impacts, such as those that can occur in contact sports or motor vehicle accidents, to improve understanding of traumatic brain injury (TBI) and enhance injury prediction models. The project will integrate dynamic MRI techniques and sonomicrometry measurements in cadaveric specimens to better quantify brain deformation (strain) at concussion-level accelerations. Experimental data from this comprehensive approach will be made publicly available to support the development of improved computational models for predicting the biomechanical response of the living human brain during TBI incidents. This research aims to advance the prevention and management of traumatic brain injuries.
Generated 2/25/25, 3:36 AM