This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), part of the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) federal grant program, supports research to better understand the relationship between inflammation, white matter injury, and insulin-like growth factor-1 (IGF-1) in neonatal intraventricular hemorrhage (IVH). The $440,066 award to the Medical University of South Carolina, with sub-awards to the University of Texas Health Science Center at Houston and the University of Kentucky Research Foundation, aims to investigate how microglia respond to IVH, the impact of hemoglobin and IGF-1 on inflammation and oligodendrocyte progenitor cell development, and the potential for IGF-1 therapy to modulate microglial activation and improve myelination following IVH. The project period runs from September 2024 through July 2029.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $440.1k | 9/18/24 |
Grant Number | Description | Subgrantee | Prime Award | Dollars Obligated (Click to sort descending) | Updated At (Click to sort ascending) |
|---|---|---|---|---|---|
A250138S002S | University Of Texas Health Science Center At Houston | Project Grant R01NS134626 | $86.0k | 12/29/24 | |
A250138S001S | The University Of Kentucky Research Foundation | Project Grant R01NS134626 | $36.8k | 11/14/24 |