This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $610,152 to Duke University to study the structural and functional connectivity of the cerebellum in individuals with post-traumatic stress disorder (PTSD) and trauma exposure. The project aims to investigate the role of cortico-cerebellar circuits in the pathophysiology of PTSD, with a focus on cerebellar subregion connectivity to cortical and subcortical regions, as well as the impact of PTSD on resting-state neural networks. This 4-year research effort, spanning from May 2025 to February 2029, may contribute to the development of neuromodulatory therapeutics for PTSD by enhancing the understanding of cerebellar involvement in threat processing and fear response. The findings could inform future interventions targeting cortico-cerebellar connections to improve clinical outcomes for individuals affected by PTSD.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| Not listed | $610.2k | 5/7/25 |