This $301,032 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research by Brown University to investigate the neurocomputational mechanisms underlying belief updating. The project aims to develop and apply a computational framework of contextual inference to measure belief updating behaviors across different neuroscience domains and relate them to real-world behaviors and mental health traits. The research will test the biological foundations of the model, focusing on how impairments to prefrontal inhibition and cortical attractor stability in schizophrenia may contribute to abnormal belief updating. The award, effective September 1, 2024, will fund this 5-year research project, which seeks to advance the understanding of typical and pathological belief formation processes.
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