This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $175,647 to the University of Pittsburgh to conduct research on biobehavioral markers of prenatal resilience associated with positive postpartum maternal mental health and well-being. The key objectives are to: 1) examine how positive childhood experiences are associated with physiological and self-reported psychological resilience in pregnancy; 2)...
The University of Illinois was awarded a $419,357 Project Grant from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research (CFDA 93.865) program. The funding will support a 2-year research project to develop interpretable machine learning models that integrate electronic medical records and neighborhood-level social determinants of health to predict perinatal depression risk among minority women of color. The goal is...
The National Institute of Mental Health (NIMH) awarded a $234,231 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the University of Pittsburgh to develop prototype machine learning algorithms to analyze longitudinal data from their prior NIMH-funded studies on juvenile-onset depression (JOD). The goal is to leverage this rich data set, which includes repeated assessments from ages 7-14 through the late 20s/early 30s, to identify risk and protective factors that predict clinical...
This Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) will support research to investigate strategies for regulating perseverative (repetitive) thought, a key symptom of internalizing psychopathology. The $107,277 award to the University of Pittsburgh will leverage mobile digital technologies and quantitative methods, including machine learning, to test and generate within-person predictions regarding the efficacy of four...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is for a study investigating the relationship between postpartum depression (PPD) and microRNA (miRNA) expression patterns of neuron-derived exosomes. The $246,306 award, with a project period from March 2025 to February 2027, will leverage existing serum samples from a longitudinal study of pregnant women to characterize miRNA patterns across pregnancy and...
The National Institutes of Health (NIH) Office of the Director awarded Carnegie Mellon University a $165,589 Project Grant under the Trans-NIH Research Support (CFDA 93.310) program. The funding will support the "Behavioral Quantification Through Active Learning and Multidimensional Physiological Monitoring" project, which aims to expand capabilities for precisely and comprehensively quantifying complex, spontaneous behaviors in mice. The project will implement an analysis pipeline...
This federal Project Grant award from the National Institutes of Health (NIH), under the Trans-NIH Research Support program (CFDA 93.310), provides $344,545 to study the development of attentional biases for affective cues in infants of mothers with depression. The award, effective from August 15, 2024 to July 31, 2029, aims to prospectively examine the influence of maternal depression on the development of infants' attentional biases for facial displays of emotion, as well as investigate...
This federal Project Grant award of $418,178 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to provide mechanistic insights into the neurobiological mechanisms by which maternal sensitivity is compromised by postpartum depression. Specifically, the University of Massachusetts (UMass), through its Office of Grant & Contract Administration, will use intersectional viral...
This Project Grant award from the National Institute of Mental Health (NIMH), under the CFDA 93.242 Mental Health Research Grants program, provides $790,712 to the University of Pittsburgh to study the impact of maternal socialization of positive emotion on child neural reward response. The research aims to characterize the mechanisms by which maternal encouragement of child positive emotion leads to changes in child reward-related brain function during the preschool years. The study will...
The National Institute of Child Health and Human Development (NICHD) awarded a 5-year, $1.3M Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the University of Illinois to conduct a clinical translational study and experimental animal model research aimed at determining the role of the microbiota-gut-brain axis (MGBA) in perinatal depression (PND). The study will recruit 158 racially diverse pregnant women (55% Black, 30% Latina) to longitudinally assess...