This federal Project Grant award of $857,216 from the National Institute of Mental Health (NIMH)'s Mental Health Research Grants program (CFDA 93.242) will support a longitudinal study on the neurodevelopmental trajectories leading to early symptoms of Attention Deficit Hyperactivity Disorder (ADHD) and Disruptive Behaviors (DBs) in a large, diverse cohort of infants and preschoolers from low-resourced families. The study will leverage an existing NINDS-funded sample to collect repeated Electroencephalogram (EEG) and behavioral data from 4 months to 4 years old. It aims to characterize the neurophysiological and environmental factors, including social determinants of health, that influence brain and behavioral development and identify potential intervention targets. The results are expected to inform the development of scalable tools for early identification of ADHD and DBs, as well as interventions tailored to individual and developmental needs. The award is held by The Children's Hospital Corporation, doing business as Boston Children's Hospital, which has extensive experience conducting federally-funded biomedical research projects.
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