Project Grant R01MH137204
Award Date
7/25/24
Completion Date
2/28/29
Dollars Obligated
$1.1M
Federal Agency
National Institute of Mental Health
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Augusta, GA 30912, USA
Similar Awards
This Project Grant award of $196,460 from the National Institute of Mental Health (NIMH) under CFDA 93.242 - Mental Health Research Grants supports a research project at Emory University to elucidate the neural mechanisms underlying novelty-related social investigation in mice. The key objectives are to: Use cellular-resolution calcium imaging to determine how social recognition information and motivated social behaviors are encoded in specific neural pathways connecting the ventral hippocampus,...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $1,122,846 to Augusta University Research Institute, Inc. to investigate the role of hippocampal HCN channels in social avoidance behaviors in male and female mice. The researchers will test hypotheses related to how changes in neuronal activity mediated by HCN channels in the hippocampal CA1 region affect susceptibility and resilience to social...
This Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) provides $1,490,348 to the Research Foundation For Mental Hygiene, Inc. (RFMH) to fund a transformative research project investigating the role of astrocytes in integrating neuromodulator signals across the brain. The key objectives are to test the hypothesis that astrocytes serve as integrators of neuromodulator inputs from systems involving serotonin, norepinephrine,...
This $2,150,657 Project Grant awarded by the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants will fund a 5-year research project to determine the developmental mechanisms that generate astrocytes, the most abundant cell type in the human brain, during cortical development. Led by Harvard University, the project aims to trace the lineage decisions of astrocytic progenitors, investigate the role of key signaling pathways and transcription factors in...
The National Institutes of Health (NIH) awarded a 5-year, $725,422 Project Grant (CFDA 93.242 Mental Health Research Grants) to the Massachusetts Institute of Technology (MIT) to investigate the role of striatal astrocytes and striosomes in modulating dopamine signaling and behavioral state transitions. The research aims to elucidate how astrocyte activity and striatal dopamine release interact to facilitate transitions between engaged and unengaged behavioral states, as well as strategy...
This federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) provides $444,125.00 to George Washington University to investigate the role of the serotonergic system in mediating the effects of early life adversity on adult social behavior. The research team will use electrophysiology, behavioral assays, and fiber photometry techniques to examine how early life stress alters the excitability of serotonergic neurons and impacts...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is focused on investigating the neural circuits and cell types that modulate social approach and avoidance behaviors. The $885,500 award, with a project period from July 2024 to June 2026, will be used by the University of California, Davis to leverage the Fast Light and Calcium-Regulated Expression (FLICRE) system to tag and genetically define the specific...
This three-year, $3.456 million project grant from the National Institute of Mental Health (NIMH) Mental Health Research Grants program (CFDA 93.242) will fund research into the role of microglia in neurodevelopmental disorders. The grantee, Cold Spring Harbor Laboratory, will merge two-photon imaging of microglia and synapses in the brains of live mice with single-cell genomics and CRISPR screens. This will help define microglia's role in experience-dependent synaptic refinement, a process...
The University of California, Irvine received a $157,000 Project Grant (Award ID: R21MH136486) from the National Institute of Mental Health (CFDA 93.242 - Mental Health Research Grants) to study the role of dopamine receptor signaling in astrocytes and its impact on prefrontal cortex functions. The researchers will use viral vectors to knock down dopamine D2 receptors specifically in astrocytes in mice with normal or altered dopamine synthesis and release. The goal is to elucidate how D2R...
This $727,479 Project Grant was awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The grant supports research to understand how sexually dimorphic (sex-differentiated) arginine vasopressin (AVP) circuits in the brain, particularly in the bed nucleus of the stria terminalis (BNST) and lateral septum (LS), influence social interest and behavior. The key objectives are to: 1) Test the necessity of V1A receptor (V1AR) cells in...