Project Grant R01MH137028
Award Date
4/15/25
Completion Date
2/28/30
Dollars Obligated
$485K
Federal Agency
National Institute of Mental Health
Federal Grant Program
93.242
Assistance Type
Project Grant
Place of Performance
Illinois, USA
Similar Awards
This Project Grant award, valued at $774,632 and running from April 1, 2025 to March 31, 2030, is funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The award supports research at Northwestern University to investigate the neural basis of dopamine-driven deficits in cognition and perception. Specifically, the project aims to use in vivo imaging to determine how activating dopamine neurons in the substantia nigra pars compacta...
This $2,306,736 federal Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) aims to reveal critical neural mechanisms for intelligent reward-driven learning and decision-making. The primary focus is on investigating how the hippocampus generates "non-local" neural representations that may be used for evaluating options (theta sequences) and updating reward values (sharp-wave-ripple events) during...
This $189,540 Project Grant award, funded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the role of cortico-striatal circuitry in model-based decision-making. The research, conducted by the University of Pittsburgh, aims to determine how model-based control is represented in specific cell types within the prelimbic cortex and dorsomedial striatum, and whether synchronization of activity between...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $553,788 to Northwestern University to conduct research on the microcircuit mechanisms behind the distributed cortical contributions to working memory. The research aims to understand how genetically identified cell types in the primary visual cortex (V1) and premotor cortex (M2) of mice interact to generate different activity timescales...
The National Institute of Mental Health (NIMH) awarded a $678,430 Project Grant (CFDA 93.242 - Mental Health Research Grants) to the University of California, Berkeley to investigate frontostriatal dynamics during decision-making. The research aims to test the hypothesis that the orbitofrontal cortex (OFC) inhibits habitual responses in the striatum to enable goal-directed behavior, particularly in the context of neuropsychiatric disorders involving compulsive behavior. The project will employ a...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $252,125 to The Trustees of Columbia University in the City of New York to conduct research on the neural mechanisms underlying context-dependent decision-making. The key objectives are to: 1) Use functional magnetic resonance imaging (fMRI) in behaving mice to identify brain regions involved in maintaining contextual information to guide...
This federal Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will support the development of a novel technique for selectively manipulating neural activity in the primate prefrontal cortex (PFC) to study its causal role in economic decision-making. The $431,750 grant, awarded to Rutgers, The State University, will be used to validate and refine a method employing multi-channel, low-current electrical...
This federal Project Grant award of $2,316,542 was issued on June 5, 2024 by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242). The grant supports research to investigate the neural basis of planning behavior, with a focus on understanding the computational strategies and neural mechanisms underlying the ability to prospectively evaluate action sequences. The research will be conducted by The Johns Hopkins University, a leading private...
This $2,286,510 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to develop a computational framework for understanding neural circuit dynamics and their role in cognition. The award to New York University will fund the development of analytical models, called Oscillatory Recurrent Gated Neural Integrator Circuits (ORGANICS), to simulate neural mechanisms underlying attention, working memory,...
This federal Project Grant award from the National Institute of Mental Health (NIMH) under CFDA 93.242 Mental Health Research Grants supports research to investigate the role of the claustrum, a subcortical brain region, in flexible decision-making and cognitive control. The $608,309 award to The Johns Hopkins University will fund studies to test whether claustrocortical neural circuits contribute to generating and maintaining persistent cortical activity required for flexible behavior in two...