This $399,365 federal Project Grant awarded by the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences (SBE) program (CFDA 47.075) aims to develop ethical guidelines for neurotechnology research to ensure its advancements enhance societal well-being. The research team will analyze existing ethics guidance, survey neurotechnology researchers on their perspectives, and provide recommendations to improve the utility and impact of ethics resources in this field. This...
This federal Project Grant award, totaling $745,822.00 and provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to investigate the role of the PERK kinase in HIV-induced neuroinflammation and neurocognitive impairment (NCI) in people with HIV (PWH). The University of Pennsylvania, as the primary grantee, will use biochemical, cellular, and pharmacologic approaches to assess PERK's potential as a predictive...
This $298,684 Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), will support a research project focused on improving the incorporation of patient and user perspectives in the design of neurotechnology. The project aims to: 1) examine adverse user experiences with non-human-centered neurotechnology design, 2) assess attitudes and barriers to adopting human-centered design among neurotechnology developers, and 3)...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is focused on investigating the roles and mechanisms of epitranscriptomic regulation in the development and function of the mammalian nervous system. The $985,026 award, effective December 23, 2024 through November 30, 2032, supports three interrelated research projects: 1) examining the...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants (CFDA 93.242) program, provides $162,486 to The Trustees of the University of Pennsylvania to investigate the relationship between functional brain development and transdiagnostic psychopathology risk. The key research objectives are to: 1) examine how deviations in the principal hierarchy of cortical functional organization relate to transdiagnostic clinical psychopathology, and...
This federal Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, is providing $220,244 to The Trustees of the University of Pennsylvania to conduct research on using functional brain imaging to detect and predict consciousness recovery in patients with acute brain injury. The key objectives are to: 1) investigate how brain network connectivity...
The federal Project Grant award of $777,537 was granted by the Defense Health Agency under the Military Medical Research and Development (CFDA 12.420) program to The Trustees of the University of Pennsylvania, doing business as the Clinical Practices of the University of Pennsylvania. The award supports research to investigate associations between blood-based neurodegenerative biomarker trajectories and the risk of epilepsy, post-traumatic epilepsy, and dementia. This 3-year research project,...
This federal Project Grant award of $606,548 from the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) will support the development of a new "mesoscopic electrophysiology" recording system at the University of Pittsburgh. The goal is to create a 3-dimensional grid of 1,920 intracranial electrode contacts across an entire brain hemisphere to enable full-brain,...
This federal Project Grant award from the National Institute of Mental Health (CFDA 93.242 Mental Health Research Grants) provides $633,438 to New York University to develop a data-driven framework for real-time neural control and targeted modulation of primate prefrontal cortical circuits. The research aims to uncover the principles governing multi-electrode microstimulation effects, develop a predictive control algorithm to evoke specific neural activity states, and explore how prefrontal...
This Project Grant award from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $231,325 to support research on the neurophysiological signatures of essential tremor and the effects of deep brain stimulation (DBS) on these neural dynamics. The primary awardee, The Trustees of the University of Pennsylvania, will use multimodal neurophysiology techniques,...