Project Grant R01HL185474

The National Heart, Lung, and Blood Institute awarded Brigham & Women's Hospital Inc. $908,994 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to test implementation strategies for electronic health record-based interventions to improve hypertension control in primary care settings.

The project builds on the recipient's prior NIH-funded REDUCE-BP trial, which enrolled 49,210 patients and 560 primary care providers and demonstrated that multi-component EHR-based interventions—including point-of-care tools, EHR-embedded dashboards to monitor hypertension control, and social needs screening and referral tools—can achieve up to 10 millimeters of mercury systolic blood pressure reduction when actively used. The prior trial identified limited uptake as the principal barrier to effectiveness. Under this award, the research team will conduct a post-trial implementation evaluation guided by the Consolidated Framework for Implementation Research (CFIR) and Expert Recommendations for Implementing Change (ERIC) to map identified barriers to candidate implementation strategies and pilot six prioritized strategy combinations. The study will be conducted in partnership with Advocate health systems.

Performance occurs in Mission Hill, Massachusetts. The period of performance runs through May 31, 2031. This is a project grant, an assistance type under NIH's standard grant portfolio.