Project Grant R01HL184061
- The National Heart, Lung, and Blood Institute awarded East Carolina University $561,100 under the Cardiovascular Diseases Research program (CFDA 93.837) on August 15, 2026 to develop a portable photoplethysmogram (PPG) prototype device and establish a platform method for noninvasive measurement of cardiometabolic disease biomarkers. The research develops a 2-site PPG data acquisition system to derive blood pressure waveform signals and extract biomarker panels including systolic and diastolic...
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded $529,283 to JB Healthtech, Inc. on September 1, 2026, under the Trans-NIH Research Support program (CFDA 93.310) to develop and advance a dual-mode wearable continuous non-invasive blood pressure monitor for enhanced diagnosis and clinical management of preeclampsia in pregnancy. The recipient is developing NeoBP, a highly accurate continuous non-invasive blood pressure device that operates...
- The National Heart, Lung, and Blood Institute awarded $920,616 to Vena Vitals Inc. on September 24, 2025, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop VeriSleep, a wearable device for continuous, non-invasive blood pressure monitoring during sleep as a cardiovascular biomarker. The project addresses the technological gap in continuous blood pressure measurement during sleep, where current intermittent cuff-based monitors leave lengthy unmonitored gaps despite the...
- This $200,000 Project Grant awarded by the National Science Foundation (NSF) Division of Electrical, Communications and Cyber Systems under CFDA 47.041 (Engineering) aims to develop and implement a novel testing platform to evaluate the accuracy of wearable photoplethysmography-based blood pressure monitoring devices. The University of Maryland, College Park will construct a bench flow phantom that simulates physiologically relevant blood pressure, blood flow, anatomical, and optical...
- The National Heart, Lung, and Blood Institute awarded Lynntech Inc. $319,607 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop and demonstrate the feasibility of BreathWise, an AI-driven early-warning system for COPD exacerbations. BreathWise integrates multimodal physiological, behavioral, and environmental sensing with machine learning-based predictive analytics to identify COPD patients at imminent risk of exacerbation. The system continuously...
- The National Science Foundation Division of Electrical, Communications and Cyber Systems awarded $200,000 to the University of Houston on October 1, 2026, for collaborative research developing FBEP-enabled electrochemical sensors for heart failure monitoring under the Engineering program (CFDA 47.041). The research develops a wearable sensing approach for continuous monitoring of N-terminal pro-B-type natriuretic peptide in skin interstitial fluid as an alternative to intermittent blood draws...
- The National Heart, Lung, and Blood Institute awarded Environment & Health Group Inc. $314,321 on August 5, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop HeartSense.AI, a generative AI-driven mobile health solution for hypertension self-management in lower-income adults. The application describes an mHealth platform that integrates a generative AI model with home-based blood pressure monitoring, digital pill reminders, and non-physician-led telehealth to...
- The National Heart, Lung, and Blood Institute awarded Aventusoft LLC $500,000 on September 1, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to advance commercialization of HEMOLINK, a skin-adhered disposable patch for non-invasive hemodynamic monitoring. HEMOLINK is a first-in-class wearable medical device featuring a synchronous quad-sensor array designed to estimate left ventricular end-diastolic pressure (LVEDP) for remote cardiac monitoring. The patch incorporates...
- Dynocardia Inc. received a $256,000 National Science Foundation Project Grant to advance development of a novel continuous, cuffless blood pressure monitoring device. Funded through the NSF Engineering Directorate's SBIR program, the award will support Dynocardia's efforts to address motion artifacts and enable accurate, beat-to-beat blood pressure measurements in hospital intensive care and operating room settings. Accurate 24-hour blood pressure monitoring has potential to significantly...
- The National Heart, Lung, and Blood Institute awarded $351,388 to Barron Associates, Inc. on August 15, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a noninvasive hemodynamic monitoring tool for heart failure patients. The project addresses the clinical gap in home and hospital monitoring of acute decompensated heart failure by creating a low-cost alternative to invasive right heart catheterization and costly implantable devices. The proposed solution...
The National Heart, Lung, and Blood Institute awarded Texas A&M Engineering Experiment Station $706,159 on August 19, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to develop a smart wearable continuous cuffless blood pressure, cardiac, and respiratory monitoring system agnostic to skin tone. The recipient will design and build an innovative wearable device integrating multiple non-invasive physiological sensors on the wrist to provide health-grade continuous cuffless blood pressure monitoring across diverse populations of skin tones and body mass index levels, with simultaneous estimation of heart rate and respiratory rate. The wearable device will integrate a quad design for strain gauge sensors, dual temperature sensors, altimetry and inertial measurements, and wireless communication via Bluetooth. In parallel, the recipient will develop deep learning algorithms to estimate cuffless blood pressure from the sensor array data, addressing current limitations of photoplethysmography-based wearable approaches that exhibit high error rates across different skin tones and body types. The period of performance extends from August 19, 2026, through April 30, 2030. Performance occurs in College Station, Texas.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $706.2k | 8/20/26 |