Project Grant R01HL176569
- This $1,380,474 federal Project Grant awarded on September 24, 2025 by the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to improve the care of patients with acute heart and lung diseases. The University of Michigan will develop data-driven models to support improved decision-making for intensive care unit (ICU) triage and inpatient bed assignment. The project will identify determinants of triage and bed assignment, develop a clinical decision...
- This federal Project Grant award of $169,344 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to advance the management of critically ill adults with non-ARDS acute hypoxemic respiratory failure (NAHRF). The key objectives are to: 1) Develop clinical prediction models for mortality in NAHRF patients; 2) Apply machine learning to detect NAHRF subphenotypes associated with differential clinical outcomes; and 3) Use sequencing-based whole...
- This federal Project Grant award, valued at $272,226.00, was granted by the National Heart Lung and Blood Institute under the Cardiovascular Diseases Research program (CFDA 93.837). The project aims to determine how clinician and scheduling characteristics impact patient outcomes, and explore the moderating effect of patient characteristics on these relationships, for mechanically ventilated adults in intensive care units. The project will conduct a novel secondary analysis utilizing a unique...
- This Project Grant award from the National Heart Lung and Blood Institute, under the Cardiovascular Diseases Research federal grant program (CFDA 93.837), provides $186,408 to the University of Washington to develop robust models that identify patients at high risk for persistent hypoxemic respiratory failure (HRF). The goal is to improve the ability to distinguish patients with persistent HRF early, which is critical for enrolling the highest-risk patients in clinical trials for new HRF...
- The University of Utah received a $782,289 project grant award from the National Heart, Lung, and Blood Institute's Cardiovascular Diseases Research program (CFDA 93.837) to develop machine learning models that incorporate donor lung CT images to predict the risk of severe primary graft dysfunction (PGD) in lung transplant recipients. The project aims to leverage a multi-center cohort of lung transplant data to build improved predictive models that fuse donor and recipient clinical data with...
- This Project Grant award from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $761,599.00 to Trustees of Boston University, doing business as Boston University Medical Campus, to conduct research on quantifying uncertainty to inform time-limited trials of invasive mechanical ventilation. The research aims to fill critical knowledge gaps around clinicians' ability to recognize prognostic uncertainty, optimal durations for time-limited trials,...
- This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) provides $500,660 to support the development of novel statistical methods for analyzing data from pooled longitudinal cohort studies. The overarching objective is to address challenges posed by systematically missing data and heterogeneity across cohorts, in order to improve the robustness of insights generated through these powerful research approaches. The 4-year...
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) provides $874,997 to Vanderbilt University Medical Center (VUMC) to conduct a randomized trial evaluating personalized oxygen therapy for critically ill, mechanically ventilated adults. The project aims to develop and validate a statistical model that can predict the optimal oxygen saturation target for individual patients to reduce mortality, compared to usual care....
- This Project Grant award from the National Heart, Lung, and Blood Institute (CFDA #93.837 Cardiovascular Diseases Research) supports research on factors associated with uncertainty and expectation formation in acute respiratory failure (ARF) survivors at hospital discharge. The $193,896 award to The Johns Hopkins University will fund a study of 65 ARF survivors to characterize the prevalence of bothersome uncertainty and its association with healthcare provider communication quality (Aim 1)....
- The federal Project Grant award of $180,936 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports a research project titled "Building a Sedation Minimization Culture" at the University of Colorado-Denver. The project aims to 1) understand how individual ICU staff characteristics and their shared assumptions, values, and beliefs shape their collective approaches to sedation, and 2) promote sedation minimization in the ICU by...
This federal Project Grant award of $738,154 from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to develop a novel mortality risk prediction model to accurately assess mortality risk for ICU patients across all patient groups. The key objectives are to: (1) identify mechanisms of systematic measurement error in commonly used ICU mortality risk prediction models, and (2) develop an accurate ICU mortality risk prediction model. The project will leverage data from over 100,000 patients across 23 ICUs to address critical knowledge gaps and promote high-quality ICU care and access. Duke University, a leading research institution, will serve as the primary awardee and implement this partner-guided strategy to improve prognostic accuracy in critical care medicine.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $738.2k | 9/11/25 |