This federal Project Grant award for $727,059.00 from the National Heart Lung and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837) supports research at the University of California, Los Angeles (UCLA) to investigate cellular pathways that regulate cholesterol transport and their impacts on metabolism and disease.
The primary objectives are to: 1) identify new proteins involved in nonvesicular lipid transport, 2) define the physiological functions of these cholesterol transport factors in cellular and systemic lipid metabolism and inflammation, and 3) elucidate the mechanisms and consequences of cholesterol sensor protein phosphorylation. This research aims to provide insight into the etiology and potential therapeutic interventions for metabolic diseases. The award period runs from August 1, 2024 to May 31, 2028.
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