The University of California, Los Angeles (UCLA) received a $773,259 federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The funding supports research to investigate the role of membrane cholesterol in regulating vascular inflammation, a key mechanism underlying cardiovascular disease.
Specifically, the research aims to: 1) identify novel cholesterol-responsive proteins involved in vascular inflammation, 2) define how changes in plasma membrane cholesterol affect inflammatory signaling in vascular cells, and 3) elucidate the impact of accessible plasma membrane cholesterol on vascular inflammation and cardiovascular disease. The project will leverage UCLA's expertise and facilities to conduct this comprehensive investigation over a 4-year period from December 2024 to November 2028. As a prime grantee, UCLA may also provide sub-awards to support collaborators or student researchers as part of the project.
Generated 3/4/25, 7:17 AM