Project Grant R01HL174056

Award Date 8/10/24
Completion Date 5/31/28
Dollars Obligated $2.3M
Federal Grant Program
93.837
Assistance Type
Project Grant
Place of Performance
Salt Lake City, UT 84132, USA
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The federal Project Grant award R01HL174056, totaling $2,290,407, was provided by the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant aims to advance the use of radiation as a non-invasive means of ablation for ventricular tachycardia (VT), a life-threatening cardiac arrhythmia. The key products and services to be delivered under this grant include:

  1. Determining the dose response and structural/functional effects of radiation on cardiac tissue through electrophysiology studies, MRI imaging, and histological analysis.
  2. Creating personalized computational models of ventricular arrhythmias to develop radiation targeting strategies for VT patients.
  3. Conducting non-invasive radiation ablation treatment in a pre-clinical infarct model with VT to further understand the mechanism underlying this approach.

By improving the understanding of radiation treatment for cardiac arrhythmias, this project aims to fundamentally change the management of VT patients, reducing procedure times and risks associated with traditional invasive ablation. The grant award period runs from August 10, 2024 to May 31, 2028.

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