The Ohio State University received a $777,277 Project Grant award from the National Heart, Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) to conduct research on the genetic regulation of regulatory T cells and their impact on cardiac inflammation and healing following myocardial infarction. The project aims to elucidate how genetic differences in the expression of the CD39 enzyme on regulatory T cells affect the resolution of cardiac inflammation after a heart attack. The research will leverage both mouse models and human clinical studies to characterize these mechanisms, with the goal of identifying biomarkers and therapeutic targets related to CD39 and inflammatory pathways. This award supports the research project from September 1, 2024 through June 30, 2029.
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