This Project Grant award from the National Institute on Minority Health and Health Disparities (NIMHD) under CFDA Program 93.307 Minority Health and Health Disparities Research supports a research project titled "Comparing a Novel Telehealth-Enabled Hybrid Cardiac Rehabilitation Program to Clinic-Based Cardiac Rehabilitation for Improving Patient Engagement, Functional Outcomes, and Health Equity After ACS." The $1,643,388 award, with a project period from Sep 2024 to May 2029, will be...
The National Institute of Child Health and Human Development (NICHD) awarded a 5-year, $492,869 Project Grant (CFDA 93.865 - Child Health and Human Development Extramural Research) to the Medical University of South Carolina (MUSC) to test the effects of a 12-week modified cardiac rehabilitation program on physical and psychosocial function in community-dwelling stroke survivors with and without post-stroke depression. The project, titled "Modified Cardiac Rehabilitation to Enhance...
This Project Grant award of $111,750 from the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847), supports research to refine and optimize a telephone-based coaching intervention to help individuals recover from small weight regains during weight loss maintenance. The research team at The Miriam Hospital, a non-profit hospital in Providence, Rhode Island, will use a...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $321,363 to Nucleusrx, Inc. to develop and test a virtual care platform and remote intervention tool targeting post-acute care heart failure (HF) patients. The goal is to create a solution that enables healthcare providers to implement a safe discharge transition plan from hospital to home, while allowing rapid optimization of...
This Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) will support the "SUPPORT YOUR HEART: FEASIBILITY TRIAL OF A CARDIOVASCULAR HEALTH INTERVENTION FOR YOUNG ADULTS" study. The $178,366 award from NIH, with a project period from August 1, 2025 to July 31, 2027, will fund the development and pilot testing of a telephone-based health coaching intervention for young adults to improve their cardiovascular health...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) aims to optimize an evidence-based physical activity intervention for Latina women who do not meet physical activity guidelines. The $722,190 award to Brown University will integrate components from mindfulness-based stress reduction to improve adherence to physical activity among inactive Latina participants. The study will also rigorously evaluate stress as a...
This federal Project Grant award of $792,235 from the National Heart Lung and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) supports the development and execution of a randomized clinical trial to evaluate the effectiveness of a commercially available fitness mHealth app (Rehabbing with Peloton) for improving physical activity among individuals recovering from transcatheter aortic valve replacement (TAVR). The key products and services to be delivered under this grant include:...
This federal Project Grant award of $651,380, provided by the National Heart Lung and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), supports research aimed at elucidating the molecular mechanisms by which coronary endothelial cells can survive and proliferate in ischemic conditions. The primary objectives are to investigate how reducing mitochondrial reactive oxygen species (mito-ROS) in endothelial cells, using genetic or nanoparticle approaches, can enhance oxidative...
This Project Grant award of $601,507, provided by the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research), aims to elucidate the molecular mechanisms regulating the dynamic nature and interplay between myocardial cell-cell and cell-extracellular matrix (ECM) interactions and the downstream signals that control cardiomyocyte proliferation. The award supports research conducted by Rhode Island Hospital, a division of Lifespan Corporation, to determine the...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) will provide $374,592 to the University of Rochester to support Dr. Lachant's research on an electronically-delivered rehabilitation program for patients hospitalized with acute pulmonary embolism. The goal is to evaluate whether a prescriptive exercise program can reduce post-pulmonary embolism syndrome by addressing deconditioning and anxiety. The study will...
This federal Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) is providing $940,798 to The Miriam Hospital to develop an optimized, stepped care intervention to help under-resourced patients maintain improvements in key health behaviors after completing cardiac rehabilitation. The project will utilize a sequential, multiple assignment, randomized trial (SMART) design to create an adaptive intervention that minimizes patient burden. Specifically, the research will evaluate the effectiveness of low-intensity text messaging versus an automated online program for initial adherence support, followed by an assessment of low- versus high-intensity home-based cardiac rehabilitation with or without case management for non-responders. The goal is to develop an evidence-based, personalized approach to extend the benefits of cardiac rehabilitation for vulnerable patient populations. Rhode Island Hospital is a sub-awardee on this project, providing specialized medical research and consultation services. The project commenced in August 2024 and is slated for completion by April 2029.