This $810,964 Project Grant awarded by the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, supports the development of a novel non-invasive 3D mapping technique to accurately identify the site of origin for ventricular tachycardia (VT) and premature ventricular complexes (PVCs) using 12-lead ECG data. The project aims to create a computerized method that can automatically locate the VT exit/PVC origin site in real-time,...
The University of Southern California received a $677,635 Project Grant (R56HL173809) from the National Heart, Lung, and Blood Institute (NHLBI) under the Cardiovascular Diseases Research program (CFDA 93.837). The grant aims to develop a novel generation of high-speed 4D echocardiography systems with adjustable multi-planar acquisition capabilities. The project will leverage broadband matrix array transducer technology, multi-line transmit focusing, and coherence-based beamforming to enable...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $770,000 Project Grant under CFDA 93.837 - Cardiovascular Diseases Research to the University of Utah to develop an innovative nasal transesophageal echocardiography (nasal-TEE) system. The objective is to create a nasal-TEE prototype that can acquire high-quality cardiac imaging without the need for anesthesia, which would reduce cost, improve workflow, expand availability, and enhance safety compared to conventional TEE. The...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $172,800 Project Grant under CFDA 93.837 - Cardiovascular Diseases Research to The Trustees of Columbia University in the City of New York, Health Sciences Division. The grant, awarded on July 20, 2025, will fund research to predict the hemodynamic response to mitral valve interventions using pressure-volume analysis. The research aims to: 1) identify new echocardiographic measures of left ventricular systolic function in...
This Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), provides $293,653 to 3DT Holdings, LLC to develop a software tool for optimizing cardiac resynchronization therapy (CRT), conduction system pacing (CSP), and left ventricular endocardial pacing (LVEP) therapies. The goal is to reduce non-responder rates and improve patient identification for these treatments, especially for patients with...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $295,153 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to Safebeat RX Inc. The funding supports the development of a novel, smartwatch-enabled technology that allows patients with low-risk atrial fibrillation to safely initiate antiarrhythmic medications at home. The technology analyzes post-drug ECG data taken by patients using a machine learning algorithm and provides this information to...
This Project Grant award of $1,331,984.00 from the National Heart, Lung, and Blood Institute (CFDA 93.837 - Cardiovascular Diseases Research) supports research to develop new lung quantitative ultrasound (LQUS) metrics for monitoring pulmonary edema due to heart failure and idiopathic pulmonary fibrosis. The primary awardee, North Carolina State University, will work to mitigate chest-wall effects, optimize data acquisition, and apply LQUS methods in human patients with heart failure and...
This federal Project Grant award from the National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research program (CFDA 93.837), is focused on enabling clinicians to better leverage information from carotid computed tomographic angiography (CTA) scans to assess stroke risk. The $771,485 award, effective August 1, 2025 through May 31, 2030, aims to: 1) identify reliable imaging-derived carotid plaque features associated with cryptogenic stroke, 2) develop an advanced...
The National Heart, Lung, and Blood Institute (NHLBI) awarded a $167,588 Project Grant under the Cardiovascular Diseases Research program (CFDA 93.837) to the Icahn School of Medicine at Mount Sinai (ISMMS). The grant supports the career development of Dr. Son Duong, a clinician-scientist specializing in pediatric cardiology and advanced cardiovascular imaging, into an independent investigator. The primary objectives are to: 1) Develop and validate a prediction tool for right ventricular volumes...
The National Heart, Lung, and Blood Institute (NHLBI), under the Cardiovascular Diseases Research (CFDA 93.837) program, awarded a $413,595 Project Grant to Unandup, LLC, a medical technology firm based in St. Louis, Missouri. The grant will fund the development of a magnetic rotational atherectomy platform to debulk severely calcified coronary lesions and improve percutaneous coronary intervention procedures. Key innovations include the use of magnetic fields to control the atherectomy...