This National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program Project Grant awarded to the University of California, San Diego (UCSD) provides $300,000 over a 5-year period from September 1, 2024 to August 31, 2029. The grant will fund research to explore the evolutionary development of neural cell types and visual circuits across insect species, including mosquitoes, house flies, and butterflies. The project aims to utilize the insect visual system as a model to understand...
This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) provides $507,000.00 to the University of California, Davis over a 5-year period from January 10, 2025 to December 31, 2029. The award supports research on the evolutionary and functional genomics of genetic novelties and expression adaptation in Drosophila. Specifically, the project aims to identify transcriptome novelties...
This Project Grant award, valued at $491,366, was issued by the National Human Genome Research Institute (NHGRI) under the Human Genome Research federal grant program (CFDA 93.172). The award is focused on developing new algorithms to robustly map disease-associated genetic variants to critical target genes, particularly in underrepresented populations. Key objectives include: Improving the ability to identify disease-critical genes in non-European populations where data is limited. Developing...
The National Institute of General Medical Sciences (NIGMS) awarded a $616,786 Project Grant (CFDA 93.859 Biomedical Research and Research Training) to The Regents of the University of California, San Francisco (UCSF) with a performance period from June 1, 2025 to May 31, 2030. The grant supports research aimed at uncovering the evolutionary forces that shape genetic variation and drive phenotypic diversity across human populations. Key focus areas include investigating the impacts of recessive...
This federal Project Grant award of $611,728 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) supports research into the molecular mechanisms underlying transcriptional control in the early development of the fruit fly Drosophila melanogaster. The award, effective August 1, 2024 through July 31, 2025, will be used by the University of California, Berkeley to combine advanced imaging and computational technologies to...
This $704,922 Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) supports research to elucidate the cellular and molecular functions of an ancient neural enhancer called "HAR123" and its role in human neural development and cognitive flexibility. The research is being conducted by the University of California, San Diego (UCSD) with the goal of understanding how rapid evolution of this enhancer in the...
This federal Project Grant award of $395,000 from the National Institute of General Medical Sciences (NIGMS) Biomedical Research and Research Training Program (CFDA 93.859) will fund research at Utah State University to investigate the role of structural variants in trait variation and adaptive evolution across three insect systems: Timema stick insects, Callosobruchus maculatus seed beetles, and Lycaeides butterflies. The research aims to characterize the prevalence, effects, and evolutionary...
This Project Grant award from the National Human Genome Research Institute (NHGRI), under the Human Genome Research federal grant program (CFDA 93.172), provides $757,157 to the University of California, San Diego (UC San Diego) to develop complementary experimental and computational strategies for high-throughput characterization of the impact of genetic variants. The key objectives are to: 1) Develop a method called SCBE-SEQ that combines genome editing with single-cell sequencing to...
This $1,122,664 Project Grant award from the National Science Foundation (NSF) Biological Sciences program (CFDA 47.074) will investigate how genes from microbial ancestors have evolved to produce new beneficial traits in eukaryotic organisms such as insects. The research will focus on understanding the regulatory processes that allow virus-derived genetic material to be integrated into host genomes and provide novel functionality. Key objectives include: Examining multiple natural examples of...
The University of California, San Diego (UCSD) received a $1,378,728 Project Grant award from the National Institutes of Health (NIH) under the Trans-NIH Research Support program (CFDA 93.310) to conduct research on the neural circuits underlying biological motion perception and social engagement. The project aims to investigate the development of social brain networks in the micro glassfish (Danionella cerebrum) vertebrate model, leveraging its genetic amenability, small size, and optical...