Project Grant R01HD121993
- This federal Project Grant award of $418,178 from the National Institute of Child Health and Human Development (NICHD), under the Child Health and Human Development Extramural Research program (CFDA 93.865), aims to provide mechanistic insights into the neurobiological mechanisms by which maternal sensitivity is compromised by postpartum depression. Specifically, the University of Massachusetts (UMass), through its Office of Grant & Contract Administration, will use intersectional viral...
- This federal Project Grant award from the National Institutes of Health (NIH) Office of the Director under CFDA Program 93.310 - Trans-NIH Research Support provides funding of $1,340,637 to the University of California, San Diego (UCSD) to investigate the neural mechanisms underlying the development of social behaviors in mammalian infants. The project aims to genetically identify sensory neurons that attach positive valence to maternal olfactory cues, and use spatial transcriptomics to map...
- This Project Grant award of $237,000 from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) will support research by Northeastern University to investigate the role of the hormone allopregnanolone in producing long-term alterations in brain activity and behavior related to pregnancy and motherhood. The research aims to establish a causal, mechanistic link between the hormonal changes of pregnancy and the subsequent neural and...
- This National Science Foundation project grant award of $1,444,730 provides funding from June 1, 2022 to May 31, 2026 to The Ohio State University Office of Sponsored Programs under the Biological Sciences (CFDA 47.074) federal grant program. The award will support research investigating neuroimmune contributions to maternal care during pregnancy. The grantee aims to further understanding of how pregnancy hormones impact the expectant mother's immune system and brain function to foster...
- This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under CFDA 93.865 Child Health and Human Development Extramural Research, provides $627,301 to support research on the neurosteroid allopregnanediol and its effects on promoting parental behavior. The award will fund a study to characterize the mechanisms of action of this neurosteroid, which has been shown to promote parental care in mice, in order to gain a better...
- This Project Grant award from the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865) supports research to understand the molecular and neural circuit mechanisms underlying sex- and state-dependent differences in parental behavior in animal models. The $55,774 award, spanning September 2025 to August 2028, will enable the University of Kentucky Research Foundation to rigorously assess...
- This $14.48 million cooperative agreement from the National Institutes of Health's National Institute of Neurological Disorders and Stroke will fund research into the neural dynamics driving affiliation and attachment. Awarded to the University of California, Los Angeles under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853), the project aims to examine how the neurobiology underlying affiliative behaviors in mice is adapted to support more...
- The National Institutes of Health (NIH) Office of the Director awarded Washington State University a $138,097 Project Grant under the Trans-NIH Research Support program (CFDA 93.310) on June 3, 2022. The grant will fund a study examining the effects of mother-infant brain activity coordination on emerging self-regulation by testing the synchronization hypothesis. Researchers will study the extent of neural synchronization between mothers and infants during a regulatory challenge task known as...
- This $1,988,947 Project Grant award from the National Institute of Mental Health (NIMH), under the Federal Grant Program "Mental Health Research Grants" (CFDA 93.242), will fund the development of a scalable high-throughput proteomics profiling pipeline to generate comprehensive molecular atlases of distinct brain cell types in the mouse brain. The key products and services to be delivered include: Increasing the multiplexing capability to 100-plex for antibody-based proteomic...
- This federal Project Grant award, provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), will support research to characterize a genetic mouse model for a gene implicated in neurodevelopmental disorders including autism, intellectual disability, and schizophrenia. The $742,484 award, with a project period from January 13, 2025 to October 31, 2029, will fund experiments to obtain multiome single nucleus RNA-sequencing,...
This $2,233,478 Project Grant award from the National Institutes of Health (NIH) Trans-NIH Research Support program (CFDA 93.310) will support research at the University of Iowa aimed at understanding the brain-wide electrical network adaptations that occur during pregnancy, postpartum, and parental care behaviors in mice. The research objectives are to: 1) identify brain-wide network adaptations aligned with specific parental behaviors, 2) characterize maternal brain adaptations at the network level that may reflect preparation for behavior change and socio-emotional vulnerability, and 3) examine how brain-wide networks of parental behaviors are transformed over the course of pregnancy and postpartum. The research will utilize techniques such as local field potential and spike recordings across multiple brain regions along with computational modeling to gain an unbiased view of the dynamic electrical activity underlying the profound neural plasticity associated with parenting in mammals. This 5-year award, commencing on September 1, 2025, seeks to provide critical insights into one of the most fundamental mammalian behaviors and its implications for parental and offspring health.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $1.1m | 9/16/25 | ||
| Not listed | ($39k) | 8/28/25 | ||
| Not listed | $1.2m | 8/22/25 |