GR137150S
MAJOR TASK 1: INITIATE AND MANAGE STUDY SUBTASK 1.1: HIRE AND TRAIN STUDY STAFF ADVERTISE AND INTERVIEW FOR PROJECT RELATED STAFF (E.G., GRA) 1-3 BH COORDINATE FOR SPACE ALLOCATION AND TRAINING FOR NEW STAFF 1-3 BH SUBTASK 1.2: OBTAIN & MAINTAIN ALL NECESSARY REGULATORY APPROVALS COMPLETE NIH PROGRESS REPORTS ANNUALLY BH, AS SUBTASK 1.3: ASSEMBLE AND CONVENE ADVISORY BOARD PARTNER WITH NATIONAL ORGANIZATIONS TO IDENTIFY ADDITIONAL ADVISORY BOARD MEMBERS WITH LIVED EXPERIENCE WITH ORGAN TRANSPLANTATION 1-3 LW OBTAIN INITIAL FEEDBACK FROM ADVISORY BOARD ON OVERALL STUDY DIRECTION, VARIABLE OPERATIONALIZATION, DISSEMINATION PLAN 4-6 LW LIAISE WITH NATIONAL ORGANIZATIONS TO COORDINATE ON ADVOCACY EFFORTS 2-4X ANNUALLY LB, LS LIAISE WITH PATIENT AND FAMILY STAKEHOLDERS ON AN ONGOING BASIS TO TROUBLESHOOT, KEEP THEM INFORMED OF PROGRESS 2-4X ANNUALLY LW SUBTASK 1.4: CONVENE RESEARCH TEAM MPI MEETINGS EVERY 2 WEEKS BH, AS STUDY TEAM MEETINGS MONTHLY ALL BIOSTATS PROGRESS MEETINGS EVERY 2 WEEKS JMH, BH, AS MAJOR TASK 2: CONSTRUCT AIMS 1-2 ANALYTICAL DATASETS CONSTRUCT ALL INDEPENDENT AND DEPENDENT VARIABLES AND COVARIATES 1-18 JMH, GB PERFORM PROPENSITY SCORE MATCHING 1-18 JMH, GB INITIAL DATA QUALITY CHECKS 1-18 JMH, GB MAJOR TASK 3: OBTAIN INSTITUTIONAL EMR DATA FOR AIM 3 SUBTASK 3.1: LOCAL IRB EXEMPTIONS AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT OSU 25-30 BH, AS AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT UC 25-30 LW AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT UW 25-30 LB AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT OTHER INSTITUTIONS 25-30 BH, AS SUBTASK 3.2: DATA SHARING AGREEMENTS DUA BETWEEN OSU AND UC 30-36 LW DUA BETWEEN OSU AND UW 30-36 LB DUA BETWEEN OSU AND OTHER INSTITUTIONS 30-36 BH, AS SUBTASK 3.3: SHARING DATA DATA OBTAINED FROM UC BY OSU 36 LW, BH, AS DATA OBTAINED FROM UW BY OSU 36 LB, BH, AS DATA OBTAINED FROM ANY OTHER INSTITUTIONS BY OSU 36 BH, AS MAJOR TASK 4: DATA ANALYSES SUBTASK 4.1: ANALYSES FOR AIM 1: DETERMINE THE EFFICACY OF STATE LAWS PROHIBITING ABLEIST DISCRIMINATION IN CLOSING THE EQUITY GAP BETWEEN KIDNEY TRANSPLANT CANDIDATES WITH VS. WITHOUT IDD JMH, GB DESCRIPTIVE STATISTICS AND GRAPHICAL DISPLAYS OF CROSSSECTIONAL DATA TO INSPECT NEED FOR TRANSFORMATIONS FOR SKEWED VARIABLES 19-20 JMH, GB DATA ANALYSIS AS DESCRIBED IN D.5.A OF OUR APPROACH 19-30 JMH, GB RESULTS INTERPRETATION 30 ALL SUBTASK 4.2: ANALYSES FOR AIM 2: IDENTIFY COMORBIDITIES AND SOCIAL DETERMINANTS OF HEALTH THAT COMPOUND WITH ABLEISM TO DISPROPORTIONATELY REDUCE KIDNEY TRANSPLANT ACCESS AND INCREASE DIALYSIS TIME FOR PATIENTS WITH VS. WITHOUT IDD JMH, GB DESCRIPTIVE STATISTICS AND GRAPHICAL DISPLAYS OF CROSSSECTIONAL DATA TO INSPECT NEED FOR TRANSFORMATIONS FOR SKEWED VARIABLES 31 JMH, GB DATA ANALYSIS AS DESCRIBED IN D.5.A OF OUR APPROACH 31-42 JMH, GB RESULTS INTERPRETATION 42 ALL SUBTASK 4.3 ANALYSES FOR AIM 3: COMPARE REASONS FOR EXCLUSION AMONG PATIENTS WITH VS. WITHOUT IDD ACROSS MULTIPLE LARGE MEDICAL CENTERS TO UNDERSTAND HOW ABLEISM IMPACTS ACCESS TO KIDNEY TRANSPLANTATION. UALITATIVE RECORD REVIEW OBTAINING FREQUENCY COUNTS AND ENTERING DATA INTO SPREADSHEET 37-42 BH, AS DESCRIPTIVE DATA ANALYSES 43-48 JMH, GB RESULTS INTERPRETATION 48 ALL MAJOR TASK 5: COMMUNICATION OF STUDY RESULTS TO SCIENTIFIC AND LAY COMMUNITIES SUBTASK 5.1 ANNUAL CONFERENCES PROVIDE FEEDBACK ON ABSTRACTS/CONFERENCE SUBMISSIONS ANNUALLY ALL SUBMIT ABSTRACT ON PRELIMINARY FINDINGS TO ANNUAL MEETING(S) TBD ANNUALLY BH, AS SUBTASK 5.2 PEER-REVIEWED MANUSCRIPTS PREPARE AIM 1 PAPER WITH FEEDBACK FROM ALL 31-36 BH, AS SUBMIT AIM 1 PAPER 36 BH, AS PREPARE AIM 2 PAPER WITH FEEDBACK FROM ALL 43-48 BH, AS SUBMIT AIM 2 PAPER 48 BH, AS PREPARE AIM 3 PAPER WITH FEEDBACK FROM ALL 49-54 BH, AS SUBMIT AIM 3 PAPER 54 BH, AS SUBMIT ALL PUBLISHED MANUSCRIPTS TO PUBMED CENTRAL 36-60 BH, AS SUBTASK 5.3: COMMUNICATE RESULTS TO STAKEHOLDERS INCLUDING PATIENTS WITH IDD, FAMILY MEMBERS OF PATIENTS WITH IDD, AND HEALTHCARE PROVIDERS RELEASE COMMUNITY REPORTS ON PRIMARY STU
Cincinnati Univ Of
Project Grant R01HD116245
$55.2k 10/30/24 GR137151S
MAJOR TASK 1: INITIATE AND MANAGE STUDY SUBTASK 1.1: HIRE AND TRAIN STUDY STAFF ADVERTISE AND INTERVIEW FOR PROJECT RELATED STAFF (E.G., GRA) 1-3 BH COORDINATE FOR SPACE ALLOCATION AND TRAINING FOR NEW STAFF 1-3 BH SUBTASK 1.2: OBTAIN & MAINTAIN ALL NECESSARY REGULATORY APPROVALS COMPLETE NIH PROGRESS REPORTS ANNUALLY BH, AS SUBTASK 1.3: ASSEMBLE AND CONVENE ADVISORY BOARD PARTNER WITH NATIONAL ORGANIZATIONS TO IDENTIFY ADDITIONAL ADVISORY BOARD MEMBERS WITH LIVED EXPERIENCE WITH ORGAN TRANSPLANTATION 1-3 LW OBTAIN INITIAL FEEDBACK FROM ADVISORY BOARD ON OVERALL STUDY DIRECTION, VARIABLE OPERATIONALIZATION, DISSEMINATION PLAN 4-6 LW LIAISE WITH NATIONAL ORGANIZATIONS TO COORDINATE ON ADVOCACY EFFORTS 2-4X ANNUALLY LB, LS LIAISE WITH PATIENT AND FAMILY STAKEHOLDERS ON AN ONGOING BASIS TO TROUBLESHOOT, KEEP THEM INFORMED OF PROGRESS 2-4X ANNUALLY LW SUBTASK 1.4: CONVENE RESEARCH TEAM MPI MEETINGS EVERY 2 WEEKS BH, AS STUDY TEAM MEETINGS MONTHLY ALL BIOSTATS PROGRESS MEETINGS EVERY 2 WEEKS JMH, BH, AS MAJOR TASK 2: CONSTRUCT AIMS 1-2 ANALYTICAL DATASETS CONSTRUCT ALL INDEPENDENT AND DEPENDENT VARIABLES AND COVARIATES 1-18 JMH, GB PERFORM PROPENSITY SCORE MATCHING 1-18 JMH, GB INITIAL DATA QUALITY CHECKS 1-18 JMH, GB MAJOR TASK 3: OBTAIN INSTITUTIONAL EMR DATA FOR AIM 3 SUBTASK 3.1: LOCAL IRB EXEMPTIONS AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT OSU 25-30 BH, AS AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT UC 25-30 LW AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT UW 25-30 LB AIM 3 IRB PROTOCOL SUBMISSION & EXEMPTION AT OTHER INSTITUTIONS 25-30 BH, AS SUBTASK 3.2: DATA SHARING AGREEMENTS DUA BETWEEN OSU AND UC 30-36 LW DUA BETWEEN OSU AND UW 30-36 LB DUA BETWEEN OSU AND OTHER INSTITUTIONS 30-36 BH, AS SUBTASK 3.3: SHARING DATA DATA OBTAINED FROM UC BY OSU 36 LW, BH, AS DATA OBTAINED FROM UW BY OSU 36 LB, BH, AS DATA OBTAINED FROM ANY OTHER INSTITUTIONS BY OSU 36 BH, AS MAJOR TASK 4: DATA ANALYSES SUBTASK 4.1: ANALYSES FOR AIM 1: DETERMINE THE EFFICACY OF STATE LAWS PROHIBITING ABLEIST DISCRIMINATION IN CLOSING THE EQUITY GAP BETWEEN KIDNEY TRANSPLANT CANDIDATES WITH VS. WITHOUT IDD JMH, GB DESCRIPTIVE STATISTICS AND GRAPHICAL DISPLAYS OF CROSSSECTIONAL DATA TO INSPECT NEED FOR TRANSFORMATIONS FOR SKEWED VARIABLES 19-20 JMH, GB DATA ANALYSIS AS DESCRIBED IN D.5.A OF OUR APPROACH 19-30 JMH, GB RESULTS INTERPRETATION 30 ALL SUBTASK 4.2: ANALYSES FOR AIM 2: IDENTIFY COMORBIDITIES AND SOCIAL DETERMINANTS OF HEALTH THAT COMPOUND WITH ABLEISM TO DISPROPORTIONATELY REDUCE KIDNEY TRANSPLANT ACCESS AND INCREASE DIALYSIS TIME FOR PATIENTS WITH VS. WITHOUT IDD JMH, GB DESCRIPTIVE STATISTICS AND GRAPHICAL DISPLAYS OF CROSSSECTIONAL DATA TO INSPECT NEED FOR TRANSFORMATIONS FOR SKEWED VARIABLES 31 JMH, GB DATA ANALYSIS AS DESCRIBED IN D.5.A OF OUR APPROACH 31-42 JMH, GB RESULTS INTERPRETATION 42 ALL SUBTASK 4.3 ANALYSES FOR AIM 3: COMPARE REASONS FOR EXCLUSION AMONG PATIENTS WITH VS. WITHOUT IDD ACROSS MULTIPLE LARGE MEDICAL CENTERS TO UNDERSTAND HOW ABLEISM IMPACTS ACCESS TO KIDNEY TRANSPLANTATION. QUALITATIVE RECORD REVIEW OBTAINING FREQUENCY COUNTS AND ENTERING DATA INTO SPREADSHEET 37-42 BH, AS DESCRIPTIVE DATA ANALYSES 43-48 JMH, GB RESULTS INTERPRETATION 48 ALL MAJOR TASK 5: COMMUNICATION OF STUDY RESULTS TO SCIENTIFIC AND LAY COMMUNITIES SUBTASK 5.1 ANNUAL CONFERENCES PROVIDE FEEDBACK ON ABSTRACTS/CONFERENCE SUBMISSIONS ANNUALLY ALL SUBMIT ABSTRACT ON PRELIMINARY FINDINGS TO ANNUAL MEETING(S) TBD ANNUALLY BH, AS SUBTASK 5.2 PEER-REVIEWED MANUSCRIPTS PREPARE AIM 1 PAPER WITH FEEDBACK FROM ALL 31-36 BH, AS SUBMIT AIM 1 PAPER 36 BH, AS PREPARE AIM 2 PAPER WITH FEEDBACK FROM ALL 43-48 BH, AS SUBMIT AIM 2 PAPER 48 BH, AS PREPARE AIM 3 PAPER WITH FEEDBACK FROM ALL 49-54 BH, AS SUBMIT AIM 3 PAPER 54 BH, AS SUBMIT ALL PUBLISHED MANUSCRIPTS TO PUBMED CENTRAL 36-60 BH, AS SUBTASK 5.3: COMMUNICATE RESULTS TO STAKEHOLDERS INCLUDING PATIENTS WITH IDD, FAMILY MEMBERS OF PATIENTS WITH IDD, AND HEALTHCARE PROVIDERS RELEASE COMMUNITY REPORTS ON PRIMARY ST
University Of Wisconsin System
Project Grant R01HD116245
$51.9k 10/28/24