Project Grant R01GM158929
- The University of California, Davis was awarded a $300,000 Project Grant from the National Science Foundation Division of Molecular and Cellular Biosciences. The grant falls under the Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing knowledge and understanding of major problems. Specifically, the grant will fund research from August 1, 2021 to July 31, 2023 exploring an...
- This $415,224 Project Grant award from the National Science Foundation (NSF) Biological Sciences (CFDA 47.074) program supports collaborative research by Stanford University to study the genetic and physiological adaptations that give polar bears their distinctive physical traits, such as their white fur and dark skin. The research aims to identify the specific genes responsible for these adaptations, which enable polar bears to survive in the extreme cold of the Arctic environment. Key...
- This federal Project Grant award of $367,808, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), aims to increase understanding of metabolic plasticity and stress response pathways in eusocial animals, with a focus on the ant species Harpegnathos saltator. The research project seeks to elucidate the mechanistic basis for the extreme disparity in metabolism and stress resistance observed between...
- The National Science Foundation awarded a $182,136 Project Grant to the University of California Santa Cruz under the Biological Sciences federal grant program (CFDA 47.074) for the period of September 1, 2021 through December 31, 2022. The grant funds the CAREER: Advancing a Macrosystems Framework for Climate-Phenology Coupling Through Integrated Research and Education project. The project aims to advance understanding of major problems confronting the nation by promoting progress in the...
- This Project Grant award for $268,850.00 from the National Science Foundation's Biological Sciences program (CFDA 47.074) will support a comprehensive 2-year research project titled "The Ecology of Big: A Synthesis of 40 Years of Bioenergetics from Keystone Carnivores Living Large on the Landscape" conducted by the University of California, Santa Cruz. The project aims to synthesize decades of data on the energetic demands and hunting behaviors of large (>25 kg) carnivorous mammals,...
- The National Institute of General Medical Sciences (NIGMS) awarded a $376,498 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to the University of California, San Diego (UCSD) for a 5-year research program from August 1, 2025 to July 31, 2030. The research will focus on developing new active genetic systems that can function in both germline and somatic cell contexts. This includes exploring the use of CRISPR-based gene drive systems to potentially...
- The National Science Foundation (NSF) awarded a $1,363,205 Project Grant under its Biological Sciences program (CFDA 47.074) to the University of California, San Diego (UCSD) to conduct collaborative research on oxygen transport mechanisms in elite diving mammals. The project aims to investigate differences in how oxygen is delivered to skeletal muscles in pinnipeds (e.g., sea lions) versus cetaceans (e.g., dolphins) during long-duration dives. The research team will evaluate in vivo oxygen...
- This Project Grant award of $421,829 from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) supports research to explore mechanisms of lean mass recovery and tissue regeneration in migratory birds. The goal is to leverage this natural model to discover new mechanisms associated with tissue anabolism that could inform the development of effective therapeutics for recovery from cachexia, a condition characterized by...
- This Project Grant award for $639,298.00 from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports collaborative research by the University of California, Santa Cruz to investigate how conflicting maternal and paternal cues influence the evolution of transgenerational plasticity in offspring traits. The research uses theoretical models and laboratory experiments to explore how offspring respond when parents experience different environments, and whether parents...
- The National Institute of General Medical Sciences (NIGMS) awarded a $248,975 Project Grant under the Biomedical Research and Research Training program (CFDA 93.859) to Yale University on August 28, 2025. The project, titled "Stress Response Signaling as a Metabolic Sensor in Reproduction," aims to examine how nutrient sensing alters reproductive capacity via the integrated stress response (ISR) signaling pathway and steroid hormones in the Drosophila model organism. The research...
The University of California, Santa Cruz was awarded a $300,721 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to investigate the mechanisms underlying metabolic innovation in hibernating mammals. The research project will use comparative and functional genomic approaches to study the mechanisms and evolution of hibernation across the mammalian tree, with a focus on revealing regulatory mechanisms underlying hibernation gene regulation in the brown bear as a valuable hibernation model system. Additionally, the project will directly test the translational potential of bear serum factors for modulating human adipocyte metabolism. The ultimate goal is to advance the understanding of hibernation mechanisms and identify genes, transcription factors, and signaling pathways that could be targeted in the treatment of human metabolic diseases. The award period extends from September 10, 2025 to July 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $300.7k | 9/10/25 |