Project Grant R01GM157928
- The University of Colorado-Denver was awarded a $1,998,288 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The 4-year grant, commencing on September 1, 2025, will support research to investigate the kinetics of co-translational protein folding in living cells using a novel visualization technology. Specifically, the project aims to quantify co-translational folding in diverse intracellular...
- This federal Project Grant award of $427,571.00 was provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports a research project titled "Maintenance of Cellular Memory During Replication" at the University of Colorado-Denver. The project aims to uncover the molecular determinants of cellular identity and how chromatin states are regulated across the cell cycle. Key objectives...
- This federal Project Grant award of $2,053,480.00 was provided by the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), to The Regents of the University of Colorado, doing business as the University of Colorado-Denver. The project aims to develop a novel framework for analyzing pathway interactions and pathway-phenotype associations in bulk and single-cell RNA sequencing (RNA-seq) studies. The key products or...
- This federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), provides $422,931.00 to the University of Colorado-Denver to characterize how specialized microbial metabolites mediate interactions within the human microbiome. The research aims to elucidate the role of these metabolites in enabling microbial communities to resist antimicrobial therapies, with the goal of improving...
- This $340,192 Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports the University of Colorado Anschutz Medical Campus Pharmacology and Molecular Medicine Training Program (PHARMM). The 5-year grant provides funding for 8 predoctoral students annually to obtain broad, integrative training in pharmacology and molecular medicine. The program offers a comprehensive curriculum, research...
- The National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), awarded a $339,552 Project Grant to the Trustees of the Colorado School of Mines (CSM) on September 1, 2025. The grant supports CSM's research program to investigate the structure-dynamics-function relationships that regulate the biogenesis of protein complexes, with a focus on two families of bacterial proteins - S-layers and microcompartments. The goal is to...
- This $445,000 federal project grant was awarded on January 23, 2025 by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859). The grant supports research conducted by the Beckman Research Institute of the City of Hope, a nonprofit medical research organization in California, to elucidate the molecular mechanisms by which protein arginine methylation regulates gene expression, RNA metabolism, and human biology and...
- This Project Grant award of $114,300.00 from the National Institute of General Medical Sciences (CFDA 93.859 - Biomedical Research and Research Training) supports The Regents of the University of Colorado, doing business as the University of Colorado-Denver, in conducting high-throughput experimental and computational research to identify RNA elements that regulate trafficking to midbodies. The research aims to use massively parallel reporter assays, single-molecule imaging, and machine learning...
- This Project Grant, awarded by the National Science Foundation's Biological Sciences program (CFDA 47.074), provides $900,000 in funding to The Regents of the University of Colorado from February 1, 2025 to January 31, 2028. The project focuses on uncovering the molecular mechanisms by which the DNA methyltransferase 1 (DNMT1) enzyme regulates gene silencing and the inheritance of distinct cell identities. The research will utilize structural biology, biochemistry, and cell biology methods to...
- The University of Colorado-Denver received a $553,217 Project Grant award from the National Heart, Lung, and Blood Institute (CFDA 93.837 Cardiovascular Diseases Research) on August 15, 2025. The grant supports research on the "HAT-Dependent Control of Cardiac Fibrosis" to investigate the role of epigenetic regulatory proteins in controlling the activation of cardiac fibroblasts and development of cardiac fibrosis, which contributes to diastolic dysfunction and heart failure. The...
The University of Colorado-Denver was awarded a $387,536 Project Grant from the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859) to conduct research on the molecular mechanisms of the MORF transcriptional coactivator and its role in hematological and cardiovascular diseases. The project aims to provide a comprehensive understanding of how MORF binds to specific genomic sites, regulates its enzymatic activity, and impacts signaling pathways that may be targets for therapeutic interventions. This research is expected to enhance the knowledge of the "epigenetic code" and contribute to the diagnosis, prevention, and treatment of hematological and cardiovascular diseases associated with aberrant MORF activity. The project will be performed at the University of Colorado-Denver and is scheduled for completion by August 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $387.5k | 8/21/25 |